Items where Author, Editor or other role is "Fenton, Tim"

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Number of items: 55.

A

Almubarak, Aroub Yousef I (2021) Investigating the Expression of SYCP2 in HPV associated Cancers. Master of Science by Research (MScRes) thesis, University of Kent,. (doi:10.22024/UniKent/01.02.91012) (KAR id:91012)

B

Biondo, Rosalba (2020) Generating an isogenic model of the APOBEC3A_B deletion polymorphism using CRISPR/Cas9. Master of Science by Research (MScRes) thesis, University of Kent,. (KAR id:80472)

C

Chakravarthy, Ankur, Reddin, Ian, Henderson, Stephen, Dong, Cindy, Kirkwood, Nerissa, Jeyakumar, Maxmilan, Rodriguez, Daniela Rothschild, Martinez, Natalia Gonzalez, McDermott, Jacqueline, Su, Xiaoping, and others. (2022) Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance. Nature Communications, 13 (1). Article Number 5818. ISSN 2041-1723. (doi:10.1038/s41467-022-33544-x) (KAR id:97465)

Chakravarthy, Ankur, Furness, Andrew, Joshi, Kroopa, Ghorani, Ehsan, Ford, Kirsty, Ward, Matthew J., King, Emma V., Lechner, Matt, Marafioti, Teresa, Quezada, Sergio A., and others. (2018) Pan-cancer deconvolution of tumour composition using DNA methylation. Nature Communications, 9 (1). Article Number 3220. ISSN 2041-1723. (doi:10.1038/s41467-018-05570-1) (KAR id:68522)

Chakravarthy, A, Henderson, S, Thirdborough, SM, Ottensmeier, CH, Su, X, Lechner, M, Feber, A, Thomas, GJ, Fenton, TR (2016) Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx. Journal Of Clinical Oncology, 34 (34). pp. 4132-4141. ISSN 0732-183X. (doi:10.1200/JCO.2016.68.2955) (KAR id:61500)

Campbell, J, Ryan, CJ, Brough, R, Bajrami, I, Pemberton, HN, Chong, IY, Costa-Cabral, S, Frankum, J, Gulati, A, Holme, H, and others. (2016) Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines. Cell Reports, 14 (10). pp. 2490-2501. ISSN 2211-1247. (doi:10.1016/j.celrep.2016.02.023) (KAR id:61503)

Chakravarthy, A, Henderson, S, Fenton, TR (2014) When defense turns into attack: Antiviral cytidine deaminases linked to somatic mutagenesis in HPV-associated cancer. Molecular & Cellular Oncology, 1 (1). Article Number 29914. ISSN 2372-3556. (doi:10.4161/mco.29914) (KAR id:61508)

Carrasco, DR, Fenton, TR, Sukhdeo, K, Protopopova, M, Enos, M, You, MJ, Vizio, D Di, Nogueira, C, Stommel, J, Pinkus, GS, and others. (2006) The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans. Cancer Cell, 9 (5). pp. 379-390. ISSN 1535-6108. E-ISSN 1878-3686. (doi:10.1016/j.ccr.2006.03.028) (KAR id:61524)

D

Dong, Cindy (2019) Investigating the expression and function of SYCP2 in HPV+ cancer cell lines. Master of Science by Research (MScRes) thesis, University of Kent. (KAR id:81139)

Dooner, Adam (2019) Generating Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC) gene deletions in Bladder Cancer Cell Lines. Master of Science by Research (MScRes) thesis, University of Kent,. (KAR id:80476)

F

Fenton, Tim R (2021) Accumulation of Host Cell Genetic Errors following High-Risk HPV Infection. Current Opinion in Virology, 51 . pp. 1-8. ISSN 1879-6257. (doi:10.1016/j.coviro.2021.09.001) (KAR id:90593)

Filipski, Katharina, Scherer, Michael, Zeiner, Kim N, Bucher, Andreas, Kleemann, Johannes, Jurmeister, Philipp, Hartung, Tabea I, Meissner, Markus, Plate, Karl H, Fenton, Tim R., and others. (2021) DNA methylation-based prediction of response to immune checkpoint inhibition in metastatic melanoma. Journal for ImmunoTherapy of Cancer, 9 (7). E-ISSN 2051-1426. (doi:10.1136/jitc-2020-002226) (KAR id:89373)

Ford, Kirsty, Hanley, Christopher J., Mellone, Massimiliano, Szyndralewiez, Cedric, Heitz, Freddy, Wiesel, Philippe, Wood, Oliver, Machado, Maria, Lopez, Maria-Antoinette, Ganesan, Anusha-Preethi, and others. (2020) NOX4 inhibition potentiates immunotherapy by overcoming cancer-associated fibroblast-mediated CD8 T-cell exclusion from tumours. Cancer Research, . ISSN 0008-5472. E-ISSN 1538-7445. (doi:10.1158/0008-5472.CAN-19-3158) (KAR id:80335)

Fenton, Tim R., Garrett, Michelle D., Michaelis, Martin, Wass, Mark N. (2018) Meeting Abstracts of the BACR conference: response and resistance in cancer therapy. Cancer Drug Resistance, 1 . pp. 266-302. E-ISSN 2578-532X. (doi:10.20517/cdr.2018.18) (KAR id:73043)

Fenton, Tim R., Garrett, Michelle D., Wass, Mark N., Michaelis, Martin (2018) What really matters - response and resistance in cancer therapy. Cancer Drug Resistance, 2018 (1). pp. 200-203. ISSN 2578-532X. (doi:10.20517/cdr.2018.19) (KAR id:71006)

Feber, Andrew, Worth, Daniel C., Chakravarthy, Ankur, de Winter, Patricia, Shah, Kunal, Arya, Manit, Saqib, Muhammad, Nigam, Raj, Malone, Peter R., Tan, Wei Shen, and others. (2016) CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma. Cancer Research, 76 (16). pp. 4720-4727. ISSN 0008-5472. (doi:10.1158/0008-5472.CAN-15-3134) (KAR id:61502)

Feber, A, Guilhamon, P, Lechner, M, Fenton, TR, Wilson, GA, Thirlwell, C, Morris, TJ, Flanagan, AM, Teschendorff, AE, Kelly, JD, and others. (2014) Using high-density DNA methylation arrays to profile copy number alterations. Genome Biology, 15 (2). ISSN 1474-760X. (doi:10.1186/gb-2014-15-2-r30) (KAR id:61509)

Fenton, TR, Nathanson, D, de Albuquerque, C Ponte, Kuga, D, Iwanami, A, Dang, J, Yang, H, Tanaka, K, Oba-Shinjo, SM, Uno, M, and others. (2012) Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240. Proceedings of the National Academy of Sciences, 109 (35). 14164 - 14169. ISSN 0027-8424. (doi:10.1073/pnas.1211962109) (KAR id:61514)

Feng, H, Hu, B, Jarzynka, MJ, Li, Y, Keezer, S, Johns, TG, Tang, CK, Hamilton, RL, Vuori, K, Nishikawa, R, and others. (2012) Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis. Proceedings of the National Academy of Sciences, 109 (8). pp. 3018-3023. ISSN 1091-6490. (doi:10.1073/pnas.1121457109) (KAR id:61515)

Feng, H, Hu, B, Liu, K-W, Li, Y, Lu, X, Cheng, T, Yiin, J-J, Lu, S, Keezer, S, Fenton, TR, and others. (2011) Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFR\ensuremath?-stimulated glioma tumorigenesis in mice and humans. Journal of Clinical Investigation, 121 (12). pp. 4670-4684. ISSN 0021-9738. E-ISSN 1558-8238. (doi:10.1172/JCI58559) (KAR id:61516)

Fenton, TR, Gout, IT (2010) Functions and regulation of the 70 kDa ribosomal S6 kinases. International Journal of Biochemistry and Cell Biology, 43 (1). pp. 47-59. ISSN 1357-2725. E-ISSN 1878-5875. (doi:10.1016/j.biocel.2010.09.018) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:61517)

Fenton, TR, Gwalter, J, Cramer, R, Gout, IT (2010) S6K1 is acetylated at lysine 516 in response to growth factor stimulation. Biochemical and Biophysical Research Communications, 398 (3). 400 - 405. ISSN 0006-291X. (doi:10.1016/j.bbrc.2010.06.081) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:61520)

Fenton, TR, Gwalter, J, Ericsson, J, Gout, IT (2009) Histone acetyltransferases interact with and acetylate p70 ribosomal S6 kinases in vitro and in vivo. The International Journal of Biochemistry & Cell Biology, 42 (2). 359 - 366. ISSN 1357-2725. (doi:10.1016/j.biocel.2009.11.022) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:61521)

Furnari, FB, Fenton, TR, Bachoo, RM, Mukasa, A, Stommel, JM, Stegh, A, Hahn, WC, Ligon, KL, Louis, DN, Brennan, C, and others. (2007) Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes Dev, 21 (21). pp. 2683-2710. (doi:10.1101/gad.1596707) (KAR id:61523)

Fordham-Skelton, AP, Chilley, P, Lumbreras, V, Reignoux, S, Fenton, TR, Dahm, CC, Pages, M, Gatehouse, JA (2002) A novel higher plant protein tyrosine phosphatase interacts with SNF1-related protein kinases via a KIS (kinase interaction sequence) domain. The Plant journal : for cell and molecular biology, 29 (6). pp. 705-715. ISSN 0960-7412. (doi:10.1046/j.1365-313X.2002.01250.x) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:61531)

G

Garcia, Isabella (2024) Understanding the function of the transcriptional activator ZFY in relation to its structure and evolution. Doctor of Philosophy (PhD) thesis, University of Kent,. (doi:10.22024/UniKent/01.02.107576) (KAR id:107576)

Gahadzikwa, Tanaka (2021) Investigating the potential role for RBMY in cancer. Master of Science (MSc) thesis, University of Kent,. (doi:10.22024/UniKent/01.02.92622) (KAR id:92622)

H

Hlahleni, Emmanuel Tafara (2022) ZFY:A putative transcription factor with a poorly conserved N-terminus and a highly conserved C-terminus. Master of Science by Research (MScRes) thesis, University of Kent,. (doi:10.22024/UniKent/01.02.93709) (KAR id:93709)

Holme, Harriett, Gulati, Aditi, Brough, Rachel, Fleuren, Emmy D. G., Bajrami, Ilirjana, Campbell, James, Chong, Irene Y., Costa-Cabral, Sara, Elliott, Richard, Fenton, Tim R., and others. (2018) Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness. Scientific Reports, 8 (1). ISSN 2045-2322. E-ISSN 2045-2322. (doi:10.1038/s41598-018-29043-z) (KAR id:68523)

Henderson, S, Fenton, TR (2015) APOBEC3 genes: retroviral restriction factors to cancer drivers. Trends in Molecular Medicine, 21 (5). pp. 274-284. ISSN 1471-4914. (doi:10.1016/j.molmed.2015.02.007) (KAR id:61505)

Henderson, S, Chakravarthy, A, Su, X, Boshoff, C, Fenton, TR (2014) APOBEC-Mediated Cytosine Deamination Links PIK3CA Helical Domain Mutations to Human Papillomavirus-Driven Tumor Development. Cell reports, 7 (6). pp. 1833-1841. ISSN 2211-1247. (doi:10.1016/j.celrep.2014.05.012) (KAR id:61507)

L

Leigh, James (2021) Generation and initial characterisation of parental and A3A-knockout bladder cancer cell line clones for cancer drug resistance studies. Master of Science by Research (MScRes) thesis, University of Kent,. (doi:10.22024/UniKent/01.02.91574) (KAR id:91574)

Lechner, M, Schartinger, VH, Steele, CD, Nei, WL, Ooft, ML, Schreiber, L-M, Pipinikas, CP, Chung, G T-Y, Chan, YY, Wu, F, and others. (2021) Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy. Nature Communications, 12 . Article Number 117. ISSN 2041-1723. (doi:10.1038/s41467-020-20308-8) (KAR id:85329)

Lechner, Matt, Chakravarthy, Ankur R., Walter, Vonn, Masterson, Liam, Feber, Andrew, Jay, Amrita, Weinberger, Paul M., McIndoe, Richard A., Forde, Cillian T., Chester, Kerry, and others. (2018) Frequent HPV-independent p16/INK4A overexpression in head and neck cancer. Oral Oncology, 83 . pp. 32-37. ISSN 1368-8375. (doi:10.1016/j.oraloncology.2018.06.006) (KAR id:67260)

Lechner, Matt, Vassie, Claire, Kavasogullari, Cemal, Jones, Oliver, Howard, James, Masterson, Liam, Fenton, Tim R., Yarbrough, Wendell, Waller, Jo, Gilson, Richard and others. (2018) A cross-sectional survey of awareness of human papillomavirus-associated oropharyngeal cancers among general practitioners in the UK. BMJ Open, 8 (7). Article Number e023339. ISSN 2044-6055. E-ISSN 2044-6055. (doi:10.1136/bmjopen-2018-023339) (KAR id:68524)

Lechner, M and Fenton, TR (2016) Chapter One - The Genomics, Epigenomics, and Transcriptomics of HPV-Associated Oropharyngeal Cancer - Understanding the Basis of a Rapidly Evolving Disease. In: Advances in Genetics. 1st edition. Advances in Genetics, 93 . Elsevier, pp. 1-56. ISBN 978-0-12-805217-4. E-ISBN 978-0-12-804801-6. (doi:10.1016/bs.adgen.2015.12.001) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:61504)

Lechner, M, Frampton, G, Fenton, TR, Feber, A, Palmer, G, Jay, A, Pillay, N, Forster, M, Cronin, MT, Lipson, D, and others. (2013) Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors. Genome Medicine, 5 . ISSN 1756-994X. (doi:10.1186/gm453) (KAR id:61511)

Lechner, M, Fenton, TR, West, J, Wilson, G, Feber, A, Henderson, S, Thirlwell, C, Dibra, HK, Jay, A, Butcher, L, and others. (2013) Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma. Genome Medicine, 5 (2). ISSN 1756-994X. (doi:10.1186/gm419) (KAR id:61512)

M

Ma, Jianhui, Benitez, Jorge A, Li, Jie, Miki, Sunichiro, Ponte de Alberquerque, Claudio, Galatro, Thais, Orellana, Laura, Zanca, Ciro, Reed, Rachel, Boyer, Antonia, and others. (2019) Inhibition of nuclear PTEN tyrosine phosphorylation enhances glioma radiation sensitivity through attenuated DNA repair. Cancer Cell, 35 (3). pp. 504-518. ISSN 1535-6108. (doi:10.1016/j.ccell.2019.01.020) (KAR id:72083)

Masterson, L, Lechner, M, Loewenbein, S, Mohammed, H, Davies-Husband, C, Fenton, TR, Sudhoff, H, Jani, P, Goon, P, Sterling, J and others. (2016) CD8+ T cell response to human papillomavirus 16 E7 is able to predict survival outcome in oropharyngeal cancer. European Journal of Cancer, 67 (C). pp. 141-151. ISSN 0959-8049. (doi:10.1016/j.ejca.2016.08.012) (KAR id:61501)

P

Paberzyte, Darija (2021) Exploring the Significance of the APOBEC3B Polymorphism on Cancer Risk. Master of Science by Research (MScRes) thesis, University of Kent,. (doi:10.22024/UniKent/01.02.90083) (KAR id:90083)

Periyasamy, Manikandan, Singh, Anup K., Gemma, Carolina, Kranjec, Christian, Farzan, Raed, Leach, Damien A., Navaratnam, Naveenan, Pálinkás, Hajnalka L., Vértessy, Beata G., Fenton, TR, and others. (2017) p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells. Nucleic Acids Research, 45 (19). pp. 11056-11069. ISSN 0305-1048. E-ISSN 1362-4962. (doi:10.1093/nar/gkx721) (KAR id:63515)

R

Reddin, Ian Gary, Fenton, Tim R., Wass, Mark N., Michaelis, Martin (2023) Large inherent variability in data derived from highly standardised cell culture experiments. Pharmacological research, 188 . Article Number 106671. ISSN 1096-1186. (doi:10.1016/j.phrs.2023.106671) (KAR id:99893)

Rothenburger, Tamara, McLaughlin, Katie-May, Herold, Tobias, Schneider, Constanze, Oellerich, Thomas, Rothweiler, Florian, Feber, Andrew, Fenton, Tim R., Wass, Mark N., Keppler, Oliver T., and others. (2020) SAMHD1 is a key regulator of the lineage-specific response of acute lymphoblastic leukaemias to nelarabine. Communications Biology, 3 (1). ISSN 2399-3642. (doi:10.1038/s42003-020-1052-8) (KAR id:81870)

Read, RD, Fenton, TR, Gomez, GG, Wykosky, J, Vandenberg, SR, Babic, I, Yang, H, Iwanami, A, Cavenee, WK, Mischel, PS, and others. (2013) A Kinome-Wide RNAi Screen in Drosophila Glia Reveals That the RIO Kinases Mediate Cell Proliferation and Survival through TORC2-Akt Signaling in Glioblastoma. PLoS Genetics, 9 (2). pp. 1-19. ISSN 1553-7390. E-ISSN 1553-7404. (doi:10.1249/MSS.0b013e31822cb0d2) (KAR id:61513)

Rebholz, H, Panasyuk, G, Fenton, TR, Nemazanyy, I, Valovka, T, Flajolet, M, Ronnstrand, L, Stephens, L, West, A, Gout, IT and others. (2006) Receptor association and tyrosine phosphorylation of S6 kinases. FEBS J, 273 (9). 2023 - 2036. (doi:10.1111/j.1742-4658.2006.05219.x) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:61525)

S

Smith, Nicola J., Fenton, Tim R. (2019) The APOBEC3 genes and their role in cancer: insights from human papillomavirus. Journal of Molecular Endocrinology, 64 (4). R269-R287. ISSN 0952-5041. (doi:10.1530/JME-19-0011) (KAR id:73013)

Salim, K, Fenton, TR, Bacha, J, Urien-Rodriguez, H, Bonnert, T, Skynner, HA, Watts, E, Kerby, J, Heald, A, Beer, M, and others. (2002) Oligomerization of G-protein-coupled receptors shown by selective co-immunoprecipitation. Journal of Biological Chemistry, 277 (18). pp. 15482-15485. ISSN 0021-9258. (doi:10.1074/jbc.M201539200) (KAR id:61530)

V

Vankatesan, Subramanian, Angelova, Mihaela, Puttick, Clare, Zhai, Haoran, Caswell, Deborah, Lu, Wei-Ting, Dietzen, Michelle, Galanos, Panagiotis, Evangelou, Konstantinos, Bellelli, Roberto, and others. (2021) Induction of APOBEC3 exacerbates DNA replication stress and chromosomal instability in early breast and lung cancer evolution. Cancer Discovery, . ISSN 2159-8274. E-ISSN 2159-8290. (doi:10.1158/2159-8290.CD-20-0725) (KAR id:87938)

Valovka, T, Verdier, F, Cramer, R, Zhyvoloup, A, Fenton, TR, Rebholz, H, Wang, ML, Gzhegotsky, M, Lutsyk, A, Matsuka, G, and others. (2003) Protein kinase C phosphorylates ribosomal protein S6 kinase beta II and regulates its subcellular localization. MOL CELL BIOL, 23 (3). 852 - 863. (doi:10.1128/MCB.23.3.852-863.2003) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:61528)

W

Wilson, GA, Lechner, M, and H Carén, A Köferle, Butcher, LM, Feber, A, Fenton, TR, Jay, A, Boshoff, C, Beck, S (2013) Integrated virus-host methylome analysis in head and neck squamous cell carcinoma. Epigenetics, 8 (9). pp. 953-961. ISSN 1559-2294. (doi:10.4161/epi.25614) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:61510)

Wykosky, J, Fenton, TR, Furnari, F, Cavenee, WK (2011) Therapeutic targeting of epidermal growth factor receptor in human cancer: successes and limitations. Chin J Cancer, 30 (1). pp. 5-12. (doi:10.5732/cjc.010.10542) (KAR id:61519)

Wang, M-L, Panasyuk, G, Gwalter, J, Nemazanyy, I, Fenton, TR, Filonenko, V, Gout, I (2008) Regulation of ribosomal protein S6 kinases by ubiquitination. Biochemical and Biophysical Research Communications, 369 (2). pp. 382-387. ISSN 0006-291X. (doi:10.1016/j.bbrc.2008.02.032) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:61522)

Z

Zhyvoloup, A, Nemazanyy, I, Panasyuk, G, Valovka, T, Fenton, TR, Rebholz, H, Wang, ML, Foxon, R, Lyzogubov, V, Usenko, V, and others. (2003) Subcellular localization and regulation of coenzyme a synthase. Journal of Biological Chemistry, 278 (50). 50316 - 50321. ISSN 0021-9258. (doi:10.1074/jbc.M307763200) (KAR id:61527)

Zhyvoloup, A, Nemazanyy, I, Babich, A, Panasyuk, G, Pobigailo, N, Vudmaska, M, Naidenov, V, Kukharenko, O, Palchevskii, S, Savinska, L, and others. (2002) Molecular cloning of CoA synthase - The missing link in CoA biosynthesis. Journal of Biological Chemistry, 277 (25). 22107 - 22110. ISSN 0021-9258. (doi:10.1074/jbc.C200195200) (KAR id:61529)

This list was generated on Tue Dec 24 19:34:03 2024 GMT.