Items where Author, Editor or other role is "Ortega Roldan, Jose"
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2024
| Serrano-Sanchez, Angela, Rice, Matthew Robert Edward, Cassar, Joseph, White, Lisa J., Popoola, Precious I. A., Thompson, Gary S., Hiscock, Jennifer R., Ortega-Roldan, Jose L. (2024) A solution NMR methodology enabling the elucidation of small molecule phospholipid membrane adhesion and passive permeation parameters. Chemical Communications, 60 (79). pp. 11160-11163. ISSN 1359-7345. E-ISSN 1364-548X. (doi:10.1039/d4cc01515k) (KAR id:107357) |
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| Grabauskas, Joe (2024) The Effect of Mutagenesis and Chaperone Binding on the Insertion Mechanism of Chloride Intracellular Channel 1. Master of Science by Research (MScRes) thesis, University of Kent,. (doi:10.22024/UniKent/01.02.105796) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:105796) |
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| Duah, Obed Agyemang (2024) Midbrain control of the swim behaviour of the Xenopus laevis tadpole. Master of Science by Research (MScRes) thesis, University of Kent,. (doi:10.22024/UniKent/01.02.105759) (KAR id:105759) |
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2023
| Cassar, Joseph (2023) Structural insights into the soluble form of CLIC1 and its mechanism of membrane insertion. Doctor of Philosophy (PhD) thesis, University of Kent,. (doi:10.22024/UniKent/01.02.103696) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:103696) |
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| Hilton, Kira, Tolley, Howard, Ortega-Roldan, Jose L., Thompson, Gary S., Sutton, Prof. Mark, Hind, Charlotte K., Hiscock, Jennifer R. (2023) Phospholipid headgroup composition modulates the molecular interactions and antimicrobial effects of sulfobetaine zwitterionic detergents against the “ESKAPE” pathogen Pseudomonas aeruginosa. Chemical Communications, 59 (70). pp. 10504-10507. ISSN 1359-7345. E-ISSN 1364-548X. (doi:10.1039/D3CC02320F) (KAR id:102336) |
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| Jamieson, Thomas (2023) Chloride intracellular Channel 4 as a therapeutic target in the development of pulmonary arterial hypertension. Master of Science by Research (MScRes) thesis, University of Kent. (doi:10.22024/UniKent/01.02.105785) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:105785) |
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| Anselmi, Silvia, Carvalho, Alexandra T.P., Serrano-Sanchez, Angela, Ortega-Roldan, Jose L., Caswell, Jill, Omar, Iman, Perez-Ortiz, Gustavo, Barry, Sarah M., Moody, Thomas S, Castagnolo, Daniele and others. (2023) Discovery and Rational Mutagenesis of Methionine Sulfoxide Reductase Biocatalysts To Expand the Substrate Scope of the Kinetic Resolution of Chiral Sulfoxides. ACS Catalysis, 13 (7). pp. 4742-4751. ISSN 2155-5435. (doi:10.1021/acscatal.3c00372) (KAR id:101936) |
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| Medina-Carmona, Encarnacion, Gutierrez-Rus, Luis I, Manssour-Triedo, Fadia, Newton, Matilda S, Gamiz-Arco, Gloria, Mota, Antonio J, Reiné, Pablo, Cuerva, Juan Manuel, Ortega-Muñoz, Mariano, Andrés-León, Eduardo, and others. (2023) Cell Survival Enabled by Leakage of a Labile Metabolic Intermediate. Molecular Biology and Evolution, 40 (3). Article Number msad032. ISSN 1537-1719. (doi:10.1093/molbev/msad032) (KAR id:100205) |
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| Olotu, Fisayo, Medina-Carmona, Encarnacion, Serrano Sanchez, Angela, Ossa, Felipe, El-Hamdaoui, Abdelaziz, Bishop, Özlem Tastan, Ortega-Roldan, Jose L., Abdul-Salam, Vahitha B. (2023) Structure-based discovery and in vitro validation of inhibitors of chloride intracellular channel 4 protein. Computational and Structural Biotechnology Journal, 21 . pp. 688-701. ISSN 2001-0370. (doi:10.1016/j.csbj.2022.12.040) (KAR id:99877) |
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2022
| Robley Dixon, Lucas (2022) Elucidating the difference in structure and enzymatic activity of the homologues GSTO1 and CLIC1. Master of Science by Research (MScRes) thesis, University of Kent,. (doi:10.22024/UniKent/01.02.100272) (KAR id:100272) |
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| Boles, Jessica E., Bennett, C., Baker, J., Hilton, Kira L.F., Kotak, H. A., Clark, Ewan R., Long, Y, White, Lisa J., Lai, H. Y., Hind, C. K., and others. (2022) Establishing the selective phospholipid membrane coordination, permeation and lysis properties for a series of ‘druggable’ supramolecular self-associating antimicrobial amphiphiles. Chemical Science, (33). pp. 9761-9773. ISSN 2041-6520. (doi:10.1039/D2SC02630A) (KAR id:96217) |
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| Varela, Lorena, Hendry, Alex C., cassar, Joseph, Martín-Escolano, Rubén, Cantoni, Diego, Ossa, Felipe, edwards, John C, abdul-salam, Vahitha, Ortega-Roldan, Jose L. (2022) A Zn2+-triggered two-step mechanism of CLIC1 membrane insertion and activation into chloride channels. Journal of Cell Science, 135 (15). Article Number jcs259704. ISSN 0021-9533. (doi:10.1242/jcs.259704) (KAR id:96744) |
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| Hendry, Alexandra Christina (2022) Biophysical and cellular insights into the membrane insertion mechanism of CLIC1. Doctor of Philosophy (PhD) thesis, University of Kent,. (doi:10.22024/UniKent/01.02.94117) (KAR id:94117) |
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2021
| Barker, Robert, Zec, Nebojša, Mangiapia, Gaetano, Hendry, Alex C., Koutsioubas, Alexandros, Frielinghaus, Henrich, Campana, Mario, Ortega-Roldan, Jose L., Busch, Sebastian, Moulin, Jean-François and others. (2021) Mutually Beneficial Combination of Molecular Dynamics Computer Simulations and Scattering Experiments. Membranes, 11 . Article Number 507. ISSN 2077-0375. (doi:10.3390/membranes11070507) (KAR id:89669) |
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| Newton, Jamie M., Betts, Emma L., Yiangou, Lyto, Ortega-Roldan, Jose L., Tsaousis, Anastasios D., Thompson, GS (2021) Establishing a Metabolite Extraction Method to Study the Metabolome of Blastocystis Using NMR. Molecules, 26 (11). Article Number 3285. ISSN 1420-3049. (doi:10.3390/molecules26113285) (KAR id:88372) |
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2020
| Medina-Carmona, Encarnacion, Varela, Lorena, Hendry, Alex C., Thompson, Gary S., White, Lisa J., Boles, Jessica E., Hiscock, Jennifer R., Ortega-Roldan, Jose L. (2020) A quantitative assay to study the lipid selectivity of membrane-associated systems using solution NMR. Chemical Communications, 56 (78). pp. 11665-11668. ISSN 1359-7345. (doi:10.1039/D0CC03612A) (KAR id:82527) |
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| Townshend, Georgina, Thompson, Gary, White, Lisa J., Hiscock, Jennifer R., Ortega-Roldan, Jose L. (2020) The elucidation of phospholipid bilayer-small molecule interactions using a combination of phospholipid nanodiscs and solution state NMR techniques. Chemical Communications, . ISSN 1359-7345. (doi:10.1039/C9CC09948D) (KAR id:80365) |
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| Hilton, Bradley (2020) Optimisation of the expression of Sigma Non-Opioid Intracellular Receptor 1 (o1) in membrane mimetic systems. Master of Science by Research (MScRes) thesis, University of Kent,. (KAR id:80462) |
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2019
| Varela, Lorena, Hendry, Alex C., Medina-Carmona, Encarnacion, Cantoni, Diego, Ortega-Roldan, Jose L. (2019) Membrane insertion of soluble CLIC1 into active chloride channels is triggered by specific divalent cations. bioRxiv, . Article Number 638080. (doi:10.1101/638080) (KAR id:84591) |
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| Newton, Jamie (2019) Establishing a metabolite extraction protocol and elucidating the fate of pyruvate in Blastocystis. Master of Science by Research (MScRes) thesis, University of Kent, University of Kent. (KAR id:80944) |
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| Townshend, Georgina (2019) Study of interactions between novel Supramolecular Self-associating Antimicrobials (SSAs) and phospholipid bilayer Nanodiscs. Master of Science by Research (MScRes) thesis, University of Kent,. (KAR id:80875) |
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2018
| Ortega-Roldan, Jose L. and Blackledge, Martin and Ringkjøbing Jensen, Malene (2018) Characterizing Protein-Protein Interactions Using Solution NMR Spectroscopy. In: Marsh, Joseph A., ed. Protein Complex Assembly: Methods and Protocols. Methods in Molecular Biology . Humana Press. ISBN 978-1-4939-7758-1. (doi:10.1007/978-1-4939-7759-8_5) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:69896) |
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2017
| Ossa, Felipe, Schnell, Jason R, Ortega-Roldan, Jose L. (2017) A Review of the Human Sigma-1 Receptor Structure. Advances in experimental medicine and biology, 964 . pp. 15-29. ISSN 0065-2598. (doi:10.1007/978-3-319-50174-1_3) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:61304) |
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2015
| Ortega-Roldan, Jose L., Ossa, Felipe, Amin, Nader T., Schnell, Jason R. (2015) Solution NMR studies reveal the location of the second transmembrane domain of the human sigma-1 receptor. FEBS Letters, 589 (5). pp. 659-665. ISSN 0014-5793. (doi:10.1016/j.febslet.2015.01.033) (KAR id:58599) |
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2013
| Ortega-Roldan, Jose L., Casares, Salvador, Ringkjøbing Jensen, Malene, Cárdenes, Nayra, Bravo, Jerónimo, Blackledge, Martin, Azuaga, Ana I., van Nuland, Nico A. J. (2013) Distinct Ubiquitin Binding Modes Exhibited by SH3 Domains: Molecular Determinants and Functional Implications. PLoS ONE, 8 (9). e73018. ISSN 1932-6203. (doi:10.1371/journal.pone.0073018) (KAR id:62500) |
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| Ortega-Roldan, Jose L., Ossa, F., Schnell, J. R. (2013) Characterization of the Human Sigma-1 Receptor Chaperone Domain Structure and Binding Immunoglobulin Protein (BiP) Interactions. Journal of Biological Chemistry, 288 (29). pp. 21448-21457. ISSN 0021-9258. (doi:10.1074/jbc.M113.450379) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:58602) |
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| Ceregido, M. Angeles, Garcia-Pino, Abel, Ortega-Roldan, Jose L., Casares, Salvador, López Mayorga, Obdulio, Bravo, Jeronimo, van Nuland, Nico A. J., Azuaga, Ana I. (2013) Multimeric and differential binding of CIN85/CD2AP with two atypical proline-rich sequences from CD2 and Cbl-b*. FEBS Journal, 280 (14). pp. 3399-3415. ISSN 1742-464X. E-ISSN 1742-4658. (doi:10.1111/febs.12333) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:62499) |
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| Guerry, Paul, Salmon, Loïc, Mollica, Luca, Ortega-Roldan, Jose L., Markwick, Phineus, van Nuland, Nico A J, McCammon, J Andrew, Blackledge, Martin (2013) Mapping the population of protein conformational energy sub-states from NMR dipolar couplings. Angewandte Chemie International Edition, 52 (11). pp. 3181-3185. ISSN 1521-3773. E-ISSN 1521-3773. (doi:10.1002/anie.201209669) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:61838) |
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2012
| Salmon, Loïc, Pierce, Levi, Grimm, Alexander, Ortega-Roldan, Jose L., Mollica, Luca, Jensen, Malene Ringkjøbing, van Nuland, Nico, Markwick, Phineus R. L., McCammon, J. Andrew, Blackledge, Martin and others. (2012) Multi-Timescale Conformational Dynamics of the SH3 Domain of CD2-Associated Protein using NMR Spectroscopy and Accelerated Molecular Dynamics. Angewandte Chemie International Edition, 51 (25). pp. 6103-6106. ISSN 1433-7851. E-ISSN 1521-3773. (doi:10.1002/anie.201202026) (KAR id:62501) |
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2011
| Jensen, Malene Ringkjøbing, Ortega-Roldan, Jose L., Salmon, Loïc, van Nuland, Nico, Blackledge, Martin (2011) Characterizing weak protein–protein complexes by NMR residual dipolar couplings. European Biophysics Journal, 40 (12). pp. 1371-1381. ISSN 0175-7571. E-ISSN 1432-1017. (doi:10.1007/s00249-011-0720-5) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:62502) |
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| Ortega-Roldan, Jose L., Blackledge, Martin, van Nuland, Nico A. J., Azuaga, Ana I. (2011) Solution structure, dynamics and thermodynamics of the three SH3 domains of CD2AP. Journal of Biomolecular NMR, 50 (2). pp. 103-117. ISSN 0925-2738. E-ISSN 1573-5001. (doi:10.1007/s10858-011-9505-5) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:62503) |
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| Salmon, Loïc, Ortega-Roldan, Jose L., Lescop, Ewen, Licinio, Antoine, van Nuland, Nico, Jensen, Malene Ringkjøbing, Blackledge, Martin (2011) Structure, Dynamics, and Kinetics of Weak Protein-Protein Complexes from NMR Spin Relaxation Measurements of Titrated Solutions. Angewandte Chemie International Edition, 50 (16). pp. 3755-3759. ISSN 1433-7851. E-ISSN 1521-3773. (doi:10.1002/anie.201100310) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:62504) |
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2009
| Ortega-Roldan, Jose L., Jensen, Malene Ringkjøbing, Brutscher, Bernhard, Azuaga, Ana I., Blackledge, Martin, van Nuland, Nico A. J. (2009) Accurate characterization of weak macromolecular interactions by titration of NMR residual dipolar couplings: application to the CD2AP SH3-C:ubiquitin complex. Nucleic Acids Research, 37 (9). e70. ISSN 0305-1048. E-ISSN 1362-4962. (doi:10.1093/nar/gkp211) (KAR id:62505) |
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2007
| Ortega-Roldan, Jose L., Romero Romero, M. Luisa, Ora, Ari, AB, Eiso, Lopez Mayorga, Obdulio, Azuaga, Ana I., van Nuland, Nico A. J. (2007) The high resolution NMR structure of the third SH3 domain of CD2AP. Journal of Biomolecular NMR, 39 (4). pp. 331-336. ISSN 0925-2738. E-ISSN 1573-5001. (doi:10.1007/s10858-007-9201-7) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:62506) |
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