Browse by Journal

Group by: Creator's name | Item Type | Date | No Grouping

Jump to: 2020 | 2018 | 2016 | 2012 | 2011 | 2010 | 2007 | 2006 | 2005 | 2003 | 2002 | 1998

Number of items: 18.

2020

Salado, Irene G., Singh, Abhimanyu K., Moreno-Cinos, Carlos, Sakaine, Guna, Siderius, Marco, Van der Veken, Pieter, Matheeussen, An, van der Meer, Tiffany, Sadek, Payman, Gul, Sheraz, and others. (2020) Lead Optimization of Phthalazinone Phosphodiesterase Inhibitors as Novel Antitrypanosomal Compounds. Journal of Medicinal Chemistry, . ISSN 0022-2623. (doi:10.1021/acs.jmedchem.9b00985) (KAR id:80697)

2018

Blaazer, Antoni R., Singh, Abhimanyu K., de Heuvel, Erik, Edink, Ewald, Orrling, Kristina M., Veerman, Johan J. N., van den Bergh, Toine, Jansen, Chimed, Balasubramaniam, Erin, Mooij, Wouter J., and others. (2018) Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity. Journal of Medicinal Chemistry, 61 (9). pp. 3870-3888. ISSN 0022-2623. (doi:10.1021/acs.jmedchem.7b01670) (KAR id:67365)

2016

Jones, Peter, Storer, Ian, Sabnis, Yogesh A., Wakenhut, Florian M., Whitlock, Gavin A., England, Katherine S., Mukaiyama, Takasuke, Dehnhardt, Christoph M., Coe, Jotham W., Kortum, Steve W., and others. (2016) Design and Synthesis of a Pan-Janus Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin. Journal of Medicinal Chemistry, 60 (2). pp. 767-786. ISSN 0022-2623. (doi:10.1021/acs.jmedchem.6b01634) (KAR id:60028)

Skerratt, Sarah E., Andrews, Mark, Bagal, Sharan K., Bilsland, James, Brown, David, Bungay, Peter J., Cole, Susan, Gibson, Karl R, Jones, Russell, Morao, Inaki, and others. (2016) The Discovery of a Potent, Selective, and Peripherally Restricted Pan-Trk Inhibitor (PF-06273340) for the Treatment of Pain. Journal of Medicinal Chemistry, 59 (22). pp. 10084-10099. ISSN 0022-2623. (doi:10.1021/acs.jmedchem.6b00850) (KAR id:59375)

Osborne, James D., Matthews, Thomas P., McHardy, Tatiana, Proisy, Nicolas, Cheung, Kwai-Ming J., Lainchbury, Michael, Brown, Nathan, Walton, Michael I., Eve, Paul D., Boxall, Katherine J., and others. (2016) Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737). Journal of Medicinal Chemistry, 59 (11). pp. 5221-5237. ISSN 0022-2623. (doi:10.1021/acs.jmedchem.5b01938) (KAR id:58552)

2012

Lainchbury, Michael, Matthews, Thomas P., McHardy, Tatiana, Boxall, Kathy J., Walton, Michael I., Eve, Paul D., Hayes, Angela, Valenti, Melanie R., de Haven Brandon, Alexis K., Box, Gary, and others. (2012) Discovery of 3-Alkoxyamino-5-(pyridin-2-ylamino)pyrazine-2-carbonitriles as Selective, Orally Bioavailable CHK1 Inhibitors. Journal of Medicinal Chemistry, 55 (22). pp. 10229-10240. ISSN 0022-2623. (doi:10.1021/jm3012933) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:58560)

2011

Davis, Rohan A., Hofmann, Andreas, Osman, Asiah, Hall, Rebecca A., Mühlschlegel, Fritz A., Vullo, Daniela, Innocenti, Alessio, Supuran, Claudiu T., Poulsen, Sally-Ann (2011) Natural Product-Based Phenols as Novel Probes for Mycobacterial and Fungal Carbonic Anhydrases. Journal of Medicinal Chemistry, 54 (6). pp. 1682-1692. ISSN 0022-2623. (doi:10.1021/jm1013242) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:29005)

Reader, John C., Matthews, Thomas P., Klair, Suki, Cheung, Kwai-Ming J., Scanlon, Jane, Proisy, Nicolas, Addison, Glynn, Ellard, John, Piton, Nelly, Taylor, Suzanne, and others. (2011) Structure-Guided Evolution of Potent and Selective CHK1 Inhibitors through Scaffold Morphing. Journal of Medicinal Chemistry, 54 (24). pp. 8328-8342. ISSN 0022-2623. (doi:10.1021/jm2007326) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:58567)

2010

McHardy, Tatiana, Caldwell, John J., Cheung, Kwai-Ming, Hunter, Lisa J., Taylor, Kevin, Rowlands, Martin, Ruddle, Ruth, Henley, Alan, de Haven Brandon, Alexis, Valenti, Melanie, and others. (2010) Discovery of 4-Amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides As Selective, Orally Active Inhibitors of Protein Kinase B (Akt). Journal of Medicinal Chemistry, 53 (5). pp. 2239-2249. ISSN 0022-2623. (doi:10.1021/jm901788j) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:58574)

Caldwell, John J., Welsh, Emma J., Matijssen, Cornelis, Anderson, Victoria E., Antoni, Laurent, Boxall, Kathy, Urban, Frederique, Hayes, Angela, Raynaud, Florence I., Rigoreau, Laurent J. M., and others. (2010) Structure-Based Design of Potent and Selective 2-(Quinazolin-2-yl)phenol Inhibitors of Checkpoint Kinase 2. Journal of Medicinal Chemistry, 54 (2). pp. 580-590. ISSN 0022-2623. (doi:10.1021/jm101150b) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:58571)

2007

Bunnage, Mark E., Blagg, Julian, Steele, John, Owen, Dafydd R., Allerton, Charlotte M.N., McElroy, Andrew B., Miller, Duncan, Ringer, Tracy, Butcher, Ken, Beaumont, Kevin C., and others. (2007) Discovery of potent & selective inhibitors of activated thrombin-activatable fibrinolysis inhibitor for the treatment of thrombosis. Journal of Medicinal Chemistry, 50 (24). pp. 6095-6103. ISSN 0022-2623. (doi:10.1021/jm0702433) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:34255)

Fish, Paul V., Barber, Christopher G., Brown, David G., Butt, Richard, Collis, Michael G., Dickinson, Roger P., Henry, Brian T., Horne, Valerie A., Huggins, John P., King, Elizabeth, and others. (2007) Selective Urokinase-Type Plasminogen Activator Inhibitors. 4. 1-(7-sulfonamidoisoquinolinyl)guanidines. Journal of Medicinal Chemistry, 50 (10). pp. 2341-51. ISSN 0022-2623. (doi:10.1021/jm061066t) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:34256)

Surfraz, M. Bashir-Uddin, King, Robert C., Mather, Stephen J., Biagini, Stefano C. G., Blower, Philip J. (2007) Trifluoroacetyl-HYNIC peptides: Synthesis and Tc-99m radiolabeling. Journal of Medicinal Chemistry, 50 (6). pp. 1418-1422. ISSN 0022-2623. (doi:10.1021/jm061274l) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:3105)

2006

Zhang, Han-Zhong, Zhang, Hong, Kemnitzer, William, Tseng, Ben, Cinatl, Jindrich, Michaelis, Martin, Doerr, Hans Wilhelm, Cai, Sui Xiong (2006) Design and synthesis of dipeptidyl glutaminyl fluoromethyl ketones as potent severe acute respiratory syndrome coronovirus (SARS-CoV) inhibitors. Journal of Medicinal Chemistry, 49 (3). pp. 1198-201. ISSN 0022-2623. (doi:10.1021/jm0507678) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:34100)

2005

Hoever, Gerold, Baltina, Lidia, Michaelis, Martin, Kondratenko, Rimma, Baltina, Lia, Tolstikov, Genrich A, Doerr, Hans Wilhelm, Cinatl, Jindrich (2005) Antiviral activity of glycyrrhizic acid derivatives against SARS-coronavirus. Journal of Medicinal Chemistry, 48 (4). pp. 1256-9. ISSN 0022-2623. (doi:10.1021/jm0493008) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:34111)

2003

Greenland, William E. P., Howland, Kevin, Hardy, Judith, Fogelman, Ignac, Blower, Philip J. (2003) Solid-phase synthesis of peptide radiopharmaceuticals using Fmoc-N-epsilon-(hynic-Boc)-lysine, a technetium-binding amino acid: application to Tc-99m-labeled salmon calcitonin. Journal of Medicinal Chemistry, 46 (9). pp. 1751-1757. ISSN 0022-2623. (doi:10.1021/jm030761n) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:7163)

2002

Maurer, Richard I., Blower, Philip J., Dilworth, Jonathan R., Reynolds, Christopher A., Zheng, Yifan, Mullen, Gregory E. D. (2002) Studies on the mechanism of hypoxic selectivity in copper bis(thiosemicarbazone) radiopharmaceuticals. Journal of Medicinal Chemistry, 45 (7). pp. 1420-1431. ISSN 0022-2623. (doi:10.1021/jm0104217) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:7169)

1998

Jacobson, K A, Kim, Y C, Wildman, Scott S.P., Mohanram, A, Harden, T K, Boyer, J L, King, B F, Burnstock, G (1998) A pyridoxine cyclic phosphate and its 6-azoaryl derivative selectively potentiate and antagonize activation of P2X1 receptors. Journal of Medicinal Chemistry, 41 (13). pp. 2201-2206. ISSN 0022-2623. E-ISSN 1520-4804. (doi:10.1021/jm980183o) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:52955)

This list was generated on Thu Apr 25 22:53:23 2024 BST.