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Molecular diagnosis with the corresponding clinical symptoms of canine distemper virus infection in javan leopard (Panthera pardus ssp. melas)

Rahman, Dede Aulia, Saepuloh, Uus, Santosa, Yanto, Darusman, Huda Shalahudin, Romaria Pinondang, Irene Margareth, Kindangen, Andy Sean, Pertiwi, Amira Putri, Sari, Lana, Irawan, Andi, Sultan, Keni, and others. (2022) Molecular diagnosis with the corresponding clinical symptoms of canine distemper virus infection in javan leopard (Panthera pardus ssp. melas). Heliyon, 8 (11). Article Number e11341. ISSN 2405-8440. (doi:10.1016/j.heliyon.2022.e11341) (KAR id:98294)

Abstract

Diseases are one of the possible threats to the conservation of wild cat populations. One disease that has been reported to infect and cause death, including in various wildlife, is the canine distemper virus (CDV). Here, we report the first case of CDV in an adolescent melanistic Javan female leopard in Indonesia. We combined the clinical report with the Reverse Transcription PCR (RT-PCR) analyses on the faecal and brain samples of partial nucleoprotein (CDV-N) and hemagglutinin (CDV-H) genes. We also performed analyses of urine, haematology, and blood chemistry. The nucleotide sequence confirmed the CDV infection in the female leopard and was clustered to the CDV's Asia 1 genotype. This finding opens an investigating window to analyse the pathogen transmission between animals in wildlife, particularly to support the management of conservation in natural habitats in Indonesia.

Item Type: Article
DOI/Identification number: 10.1016/j.heliyon.2022.e11341
Uncontrolled keywords: Leopard, Environmental health, Canine distemper, Conservation, Diseases
Subjects: G Geography. Anthropology. Recreation > GN Anthropology
Divisions: Divisions > Division of Human and Social Sciences > School of Anthropology and Conservation > DICE (Durrell Institute of Conservation and Ecology)
SWORD Depositor: JISC Publications Router
Depositing User: JISC Publications Router
Date Deposited: 02 Dec 2022 14:30 UTC
Last Modified: 27 Jan 2023 16:04 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/98294 (The current URI for this page, for reference purposes)

University of Kent Author Information

Romaria Pinondang, Irene Margareth.

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