Improving genetic management of California Condors through molecular research

Genetic management of California Condors aims to maximize the retention of genetic diversity by minimizing mean kinship within the population. Analysis of multi-locus DNA fingerprinting data identified 3 groups consisting of closely related individuals (clans) within the population. These findings were utilized to create a hypothetical previous generation of California Condors that were designated as founders and utilized for population management calculations and recommendations. We used a series of tetranucleotide microsatellite repeat loci to improve resolution of relationships and re-evaluate genetic relatedness among individuals obtained from the wild. These new results may alter kinship estimations and thus genetic management recommendations. We also have identified a genetic form of chondrodystrophy (dwarfism) in condors that appears to be inherited as an autosomal recessive allele. Taking advantage of recent progress in genome studies of domestic chickens, we are developing a genetic map of the California Condor. This work will aid in identification and characterization of candidate loci for the chondrodystrophy mutation in order to identify carriers of the chondrodystrophy allele and improve genetic management of this disease.