Refined localization of the chicken KITLG, MGP and TYR genes on GGA1 by FISH mapping using BACs

Sazanov, Alexei A and Sazanova, Anna L and Tzareva, Viktoria A and Kozyreva, Alexandra A and Smirnov, Alexandr F and Romanov, Michael N and Price, Jennifer A and Dodgson, Jerry B (2004) Refined localization of the chicken KITLG, MGP and TYR genes on GGA1 by FISH mapping using BACs. Animal Genetics, 35 (2). pp. 148-150. ISSN 0268-9146. (doi:https://doi.org/10.1111/j.1365-2052.2004.01088.x) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1111/j.1365-2052.2004.01088.x

Abstract

Source/description: The KIT ligand gene (KITLG, formerly MGF) codes for mast cell growth factor, the ligand of the tyrosine-kinase receptor encoded by the KIT locus. The deduced amino acid sequence of the chicken KITLG gene shows 53 and 52% identity to the mouse and human KITLG genes, respectively. Mammalian matrix Gla protein (MGP) is an 84-residue vitamin K-dependent protein expressed at high levels in heart, kidney and lung, and upregulated by vitamin D in bone cells. Avian MGP shows 51–56% identity to mammalian genes and is similarly expressed. Tyrosinase is responsible for limiting the final melanin content in tissues. Numerous mutations of the TYR gene lead to different forms of albinism in human and animals...

Item Type: Article
Uncontrolled keywords: chromosomes
Subjects: Q Science > QH Natural history > QH426 Genetics
Divisions: Faculties > Sciences > School of Biosciences > Biomedical Research Group
Depositing User: M. Romanov
Date Deposited: 12 Dec 2013 17:08 UTC
Last Modified: 18 Mar 2015 12:54 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/37563 (The current URI for this page, for reference purposes)
Romanov, Michael N: https://orcid.org/0000-0003-3584-4644
  • Depositors only (login required):