Refined localization of the chicken KITLG, MGP and TYR genes on GGA1 by FISH mapping using BACs

Sazanov, Alexei A, Sazanova, Anna L, Tzareva, Viktoria A, Kozyreva, Alexandra A, Smirnov, Alexandr F, Romanov, Michael N, Price, Jennifer A, Dodgson, Jerry B (2004) Refined localization of the chicken KITLG, MGP and TYR genes on GGA1 by FISH mapping using BACs. Animal Genetics, 35 (2). pp. 148-150. ISSN 0268-9146. (doi:10.1111/j.1365-2052.2004.01088.x) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:37563)

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Official URL: https://doi.org/10.1111/j.1365-2052.2004.01088.x

Abstract

Source/description: The KIT ligand gene (KITLG, formerly MGF) codes for mast cell growth factor, the ligand of the tyrosine-kinase receptor encoded by the KIT locus. The deduced amino acid sequence of the chicken KITLG gene shows 53 and 52% identity to the mouse and human KITLG genes, respectively. Mammalian matrix Gla protein (MGP) is an 84-residue vitamin K-dependent protein expressed at high levels in heart, kidney and lung, and upregulated by vitamin D in bone cells. Avian MGP shows 51–56% identity to mammalian genes and is similarly expressed. Tyrosinase is responsible for limiting the final melanin content in tissues. Numerous mutations of the TYR gene lead to different forms of albinism in human and animals...

Item Type:	Article
DOI/Identification number:	10.1111/j.1365-2052.2004.01088.x
Uncontrolled keywords:	chromosomes
Subjects:	Q Science > QH Natural history > QH426 Genetics S Agriculture > SF Animal culture
Divisions:	Divisions > Division of Natural Sciences > Biosciences
Signature Themes:	Food Systems, Natural Resources and Environment
Depositing User:	Mike Romanov
Date Deposited:	12 Dec 2013 17:08 UTC
Last Modified:	08 Sep 2023 16:50 UTC
Resource URI:	https://kar.kent.ac.uk/id/eprint/37563 (The current URI for this page, for reference purposes)

University of Kent Author Information

Romanov, Michael N.

Creator's ORCID:	https://orcid.org/0000-0003-3584-4644
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