da Silva Júnior, Eufrânio N., de Carvalho, Renato L., Almeida, Renata G., Rosa, Luisa G., Fantuzzi, Felipe, Rogge, Torben, Costa, Pedro M. S., Pessoa, Claudia, Jacob, Claus, Ackermann, Lutz and others. (2020) Ruthenium(II)-Catalyzed Double Annulation of Quinones: Step-Economical Access to Valuable Bioactive Compounds. Chemistry - A European Journal, 26 (48). pp. 10981-10986. ISSN 0947-6539. (doi:10.1002/chem.202001434) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:98544)
The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication) | |
Official URL: https://doi.org/10.1002/chem.202001434 |
Abstract
Double ruthenium(II)-catalyzed alkyne annulations of quinones were accomplished. Thus, a strategy is reported that provides step-economical access to valuable quinones with a wide range of applications. C−H/N−H activations for alkyne annulations of naphthoquinones provided challenging polycyclic quinoidal compounds by forming four new bonds in one step. The singular power of the thus-obtained compounds was reflected by their antileukemic activity.
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