da Silva Júnior, Eufrânio N., de Carvalho, Renato L., Almeida, Renata G., Rosa, Luisa G., Fantuzzi, Felipe, Rogge, Torben, Costa, Pedro M. S., Pessoa, Claudia, Jacob, Claus, Ackermann, Lutz and others. (2020) Ruthenium(II)-Catalyzed Double Annulation of Quinones: Step-Economical Access to Valuable Bioactive Compounds. Chemistry - A European Journal, 26 (48). pp. 10981-10986. ISSN 0947-6539. (doi:10.1002/chem.202001434) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:98544)
| The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. | |
| Contact us about this publication | |
| Official URL: https://doi.org/10.1002/chem.202001434 |
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Abstract
Double ruthenium(II)-catalyzed alkyne annulations of quinones were accomplished. Thus, a strategy is reported that provides step-economical access to valuable quinones with a wide range of applications. C−H/N−H activations for alkyne annulations of naphthoquinones provided challenging polycyclic quinoidal compounds by forming four new bonds in one step. The singular power of the thus-obtained compounds was reflected by their antileukemic activity.
| Item Type: | Article |
|---|---|
| DOI/Identification number: | 10.1002/chem.202001434 |
| Institutional Unit: | Schools > School of Natural Sciences > Chemistry and Forensic Science |
| Former Institutional Unit: |
Divisions > Division of Natural Sciences > Chemistry and Forensics
|
| Funders: |
National Council for Scientific and Technological Development (https://ror.org/03swz6y49)
Alexander von Humboldt Foundation (https://ror.org/012kf4317) Deutsche Forschungsgemeinschaft (https://ror.org/018mejw64) Deutscher Akademischer Austauschdienst (https://ror.org/039djdh30) Coordenação de Aperfeicoamento de Pessoal de Nível Superior (https://ror.org/00x0ma614) |
| Depositing User: | Felipe Fantuzzi |
| Date Deposited: | 30 Nov 2022 19:06 UTC |
| Last Modified: | 22 Jul 2025 09:13 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/98544 (The current URI for this page, for reference purposes) |
University of Kent Author Information
Fantuzzi, Felipe.
| Creator's ORCID: |
 https://orcid.org/0000-0002-8200-8262
|
|---|---|
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