Mayora-Neto, Martin, Wright, Edward, Temperton, Nigel J., Soema, Peter, ten Have, Rimko, Ploemen, Ivo, Scott, Simon D. (2022) Application and comparison of lyophilisation protocols to enhance stable long-term storage of filovirus pseudotypes for use in antibody neutralisation tests. Journal of Applied Microbiology, . E-ISSN 1365-2672. (doi:10.1093/jambio/lxac067) (KAR id:97831)
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Official URL: https://doi.org/10.1093/jambio/lxac067 |
Abstract
Filoviruses encompass highly pathogenic viruses placing significant public health burden on countries affected. Efforts for improved diagnostics and surveillance are needed. The requirement for high-containment can be circumvented by using pseudotype viruses (PV), which can be handled safely, in tropism, drug screening, vaccine evaluation and serosurveillance studies. We assessed stability and functionality after long-term storage of lyophilised filovirus pseudotypes for use in neutralisation assays
Item Type: | Article |
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DOI/Identification number: | 10.1093/jambio/lxac067 |
Projects: | 215 22415 |
Subjects: | Q Science > QR Microbiology > QR355 Virology |
Divisions: | Divisions > Division of Natural Sciences > Medway School of Pharmacy |
Funders: |
Medway School of Pharmacy (https://ror.org/00fa9v295)
University of Sussex (https://ror.org/00ayhx656) |
Depositing User: | Simon Scott |
Date Deposited: | 17 Nov 2022 14:28 UTC |
Last Modified: | 26 Jan 2023 11:00 UTC |
Resource URI: | https://kar.kent.ac.uk/id/eprint/97831 (The current URI for this page, for reference purposes) |
Mayora-Neto, Martin: | ![]() |
Temperton, Nigel J.: | ![]() |
Scott, Simon D.: | ![]() |
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