Mayora-Neto, Martin, Wright, Edward, Temperton, Nigel J., Soema, Peter, ten Have, Rimko, Ploemen, Ivo, Scott, Simon D. (2022) Application and comparison of lyophilisation protocols to enhance stable long-term storage of filovirus pseudotypes for use in antibody neutralisation tests. Journal of Applied Microbiology, . E-ISSN 1365-2672. (doi:10.1093/jambio/lxac067) (KAR id:97831)
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| Official URL: https://doi.org/10.1093/jambio/lxac067 |
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Abstract
Filoviruses encompass highly pathogenic viruses placing significant public health burden on countries affected. Efforts for improved diagnostics and surveillance are needed. The requirement for high-containment can be circumvented by using pseudotype viruses (PV), which can be handled safely, in tropism, drug screening, vaccine evaluation and serosurveillance studies. We assessed stability and functionality after long-term storage of lyophilised filovirus pseudotypes for use in neutralisation assays
| Item Type: | Article |
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| DOI/Identification number: | 10.1093/jambio/lxac067 |
| Projects: | 215 22415 |
| Subjects: | Q Science > QR Microbiology > QR355 Virology |
| Institutional Unit: | Schools > Medway School of Pharmacy |
| Former Institutional Unit: |
Divisions > Division of Natural Sciences > Medway School of Pharmacy
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| Funders: |
Medway School of Pharmacy (https://ror.org/00fa9v295)
Prifysgol Sussex (https://ror.org/00ayhx656) |
| Depositing User: | Simon Scott |
| Date Deposited: | 17 Nov 2022 14:28 UTC |
| Last Modified: | 22 Jul 2025 09:12 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/97831 (The current URI for this page, for reference purposes) |
University of Kent Author Information
Mayora-Neto, Martin.
| Creator's ORCID: |
 https://orcid.org/0000-0002-5331-5554
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| CReDIT Contributor Roles: |
Temperton, Nigel J..
| Creator's ORCID: |
https://orcid.org/0000-0002-7978-3815
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| CReDIT Contributor Roles: |
Scott, Simon D..
| Creator's ORCID: |
https://orcid.org/0000-0002-8290-0461
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| CReDIT Contributor Roles: |
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