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Host Sensing by Pathogenic Fungi

Sherrington, Sarah L. and Kumwenda, Pizga and Kousser, Courtney and Hall, Rebecca A. (2018) Host Sensing by Pathogenic Fungi. In: Advances in Applied Microbiology. Elsevier, pp. 159-221. (doi:10.1016/bs.aambs.2017.10.004) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:91790)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL:
https://doi.org/10.1016/bs.aambs.2017.10.004

Abstract

The ability to cause disease extends from the ability to grow within the host environment. The human host provides a dynamic environment to which fungal pathogens must adapt to in order to survive. The ability to grow under a particular condition (i.e., the ability to grow at mammalian body temperature) is considered a fitness attribute and is essential for growth within the human host. On the other hand, some environmental conditions activate signaling mechanisms resulting in the expression of virulence factors, which aid pathogenicity. Therefore, pathogenic fungi have evolved fitness and virulence attributes to enable them to colonize and infect humans. This review highlights how some of the major pathogenic fungi respond and adapt to key environmental signals within the human host.

Item Type: Book section
DOI/Identification number: 10.1016/bs.aambs.2017.10.004
Uncontrolled keywords: Nutritional immunity; pH; Candida; Cryptococcus; Aspergillus; Mucormycetes; CO2 sensing; Temperature
Subjects: Q Science > QR Microbiology
Divisions: Divisions > Division of Natural Sciences > Biosciences
Depositing User: Becky Hall
Date Deposited: 30 Nov 2021 12:05 UTC
Last Modified: 05 Nov 2024 12:57 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/91790 (The current URI for this page, for reference purposes)

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