A two-layered classifier based on the radial basis function for the screening of thalassaemia

Masala, Giovanni Luca, Golosio, B., Cutzu, R., Pola, R. (2013) A two-layered classifier based on the radial basis function for the screening of thalassaemia. Computers in Biology and Medicine, 43 (11). pp. 1724-1731. ISSN 0010-4825. (doi:10.1016/j.compbiomed.2013.08.020) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:91423)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided.
Official URL: https://doi.org/10.1016/j.compbiomed.2013.08.020

Abstract

The thalassaemias are blood disorders with hereditary transmission. Their distribution is global, with particular incidence in areas affected by malaria. Their diagnosis is mainly based on haematologic and genetic analyses. The aim of this study was to differentiate between persons with the thalassaemia trait and normal subjects by inspecting characteristics of haemochromocytometric data.

The paper proposes an original method that is useful in screening activity for thalassaemia classification. A complete working system with a friendly graphical user interface is presented.

A unique feature of the presented work is the adoption of a two-layered classification system based on Radial basis function, which improves the performance of the system.

Item Type:	Article
DOI/Identification number:	10.1016/j.compbiomed.2013.08.020
Additional information:	cited By 10
Uncontrolled keywords:	Radial basis function; Probabilistic neural network; K-Nearest neighbours; α-Thalassaemia; β-Thalassaemia
Subjects:	Q Science > QA Mathematics (inc Computing science) > QA 75 Electronic computers. Computer science
Divisions:	Divisions > Division of Computing, Engineering and Mathematical Sciences > School of Computing
Depositing User:	Amy Boaler
Date Deposited:	08 Nov 2021 12:33 UTC
Last Modified:	05 Nov 2024 12:57 UTC
Resource URI:	https://kar.kent.ac.uk/id/eprint/91423 (The current URI for this page, for reference purposes)

University of Kent Author Information

Masala, Giovanni Luca.

Creator's ORCID:	https://orcid.org/0000-0001-6734-9424
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