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Antimicrobial Handgels

Hilton, Kira (2021) Antimicrobial Handgels. Master of Research (MRes) thesis, University of Kent,. (doi:10.22024/UniKent/01.02.89810) (KAR id:89810)

Abstract

The fight against antimicrobial resistance needs new weapons. Bacteria resistant to all known antibiotics are anticipated to cause 10 million deaths by 2050. A series of novel Supramolecular Self-Associating Amphiphiles have been synthesised to add to the arsenal; either as unique antimicrobial agents or to act as drug delivery agents. The self-association properties of these compounds were studied in the gas phase, solid state and solution state using a range of physicochemical studies. These experiments included: electron spray ionisation mass spectrometry, single crystal X-ray diffraction, quantitative 1H NMR, diffusion ordered spectroscopy, tensiometry, dynamic light scattering and zeta potential. One of the novel compounds was observed to form hydrogels in aqueous salt solutions, and these gels were characterised using rheological methods.

Item Type: Thesis (Master of Research (MRes))
Thesis advisor: Hiscock, Jennifer
DOI/Identification number: 10.22024/UniKent/01.02.89810
Uncontrolled keywords: Antimicrobial, hydrogels, supramolecular, chemistry, rheology
Divisions: Divisions > Division of Natural Sciences > Physics and Astronomy
SWORD Depositor: System Moodle
Depositing User: System Moodle
Date Deposited: 16 Aug 2021 14:10 UTC
Last Modified: 09 Dec 2022 05:45 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/89810 (The current URI for this page, for reference purposes)

University of Kent Author Information

Hilton, Kira.

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