Korzelius, Jerome, van den Heuvel, Sander (2007) Replication Licensing: Oops! … I Did It Again. Current Biology, 17 (16). R630-R632. ISSN 0960-9822. (doi:10.1016/j.cub.2007.06.029) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:81300)
| The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. | |
| Official URL: https://doi.org/10.1016/j.cub.2007.06.029 |
Abstract
All eukaryotes use multiple controls to restrict DNA replication to once per cell cycle. Nevertheless, inactivation of a single gene, cul-4, causes massive re-replication in Caenorhabditis elegans. A novel study explains this dramatic phenotype by demonstrating that the CUL-4 E3 ligase simultaneously controls two critical licensing factors: CDT-1 and CDC-6.
| Item Type: | Article |
|---|---|
| DOI/Identification number: | 10.1016/j.cub.2007.06.029 |
| Subjects: | Q Science |
| Divisions: | Divisions > Division of Natural Sciences > Biosciences |
| Depositing User: | Jerome Korzelius |
| Date Deposited: | 18 May 2020 13:29 UTC |
| Last Modified: | 05 Nov 2024 12:47 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/81300 (The current URI for this page, for reference purposes) |
University of Kent Author Information
Korzelius, Jerome.
| Creator's ORCID: |
 https://orcid.org/0000-0002-8443-0192
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