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Controlled Release of Ibuprofen from Polymeric Nanoparticles

Shehata, Sara and Serpell, Christopher and Biagini, Stefano (2019) Controlled Release of Ibuprofen from Polymeric Nanoparticles. Working paper. ChemRxiv 10.26434/chemrxiv.9884114.v1. (doi:10.26434/chemrxiv.9884114.v1) (KAR id:78374)

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Official URL
http://dx.doi.org/10.26434/chemrxiv.9884114.v1

Abstract

Smart polymeric systems are required that are able to release a therapeutic drug with controlled delivery. Herein we investigated the pH triggered release of ibuprofen from a polymeric nanoparticle system prepared using ring-opening metathesis polymerisation. The co-polymerisation of ibuprofen and poly(ethylene)glycol monomers followed by self-assembly produced a nanoparticle system that was shown to be stable at neutral pH but releases ibuprofen in alkaline conditions

Item Type: Monograph (Working paper)
DOI/Identification number: 10.26434/chemrxiv.9884114.v1
Subjects: Q Science > QD Chemistry
Divisions: Divisions > Division of Natural Sciences > School of Physical Sciences
Depositing User: Christopher Serpell
Date Deposited: 07 Nov 2019 14:15 UTC
Last Modified: 13 Jul 2021 12:43 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/78374 (The current URI for this page, for reference purposes)
Serpell, Christopher: https://orcid.org/0000-0002-2848-9077
Biagini, Stefano: https://orcid.org/0000-0002-4713-5127
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