Skip to main content

Controlled Release of Ibuprofen from Polymeric Nanoparticles

Shehata, Sara and Serpell, Christopher J. and Biagini, Stefano C. G. (2019) Controlled Release of Ibuprofen from Polymeric Nanoparticles. Working paper. ChemRxiv Pre print server 10.26434/chemrxiv.9884114.v1. (Submitted) (doi:10.26434/chemrxiv.9884114.v1) (KAR id:78374)

Abstract

Smart polymeric systems are required that are able to release a therapeutic drug with controlled delivery. Herein we investigated the pH triggered release of ibuprofen from a polymeric nanoparticle system prepared using ring-opening metathesis polymerisation. The co-polymerisation of ibuprofen and poly(ethylene)glycol monomers followed by self-assembly produced a nanoparticle system that was shown to be stable at neutral pH but releases ibuprofen in alkaline conditions

Item Type: Monograph (Working paper)
DOI/Identification number: 10.26434/chemrxiv.9884114.v1
Subjects: Q Science > QD Chemistry
Divisions: Faculties > Sciences > School of Physical Sciences
Depositing User: Christopher Serpell
Date Deposited: 07 Nov 2019 14:15 UTC
Last Modified: 10 Feb 2020 09:36 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/78374 (The current URI for this page, for reference purposes)
Serpell, Christopher J.: https://orcid.org/0000-0002-2848-9077
Biagini, Stefano C. G.: https://orcid.org/0000-0002-4713-5127
  • Depositors only (login required):

Downloads

Downloads per month over past year