Controlled Release of Ibuprofen from Polymeric Nanoparticles

Shehata, Sara and Serpell, Christopher and Biagini, Stefano (2019) Controlled Release of Ibuprofen from Polymeric Nanoparticles. [Preprint] (doi:10.26434/chemrxiv.9884114.v1) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:78374)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided.
Official URL: http://dx.doi.org/10.26434/chemrxiv.9884114.v1

Abstract

Smart polymeric systems are required that are able to release a therapeutic drug with controlled delivery. Herein we investigated the pH triggered release of ibuprofen from a polymeric nanoparticle system prepared using ring-opening metathesis polymerisation. The co-polymerisation of ibuprofen and poly(ethylene)glycol monomers followed by self-assembly produced a nanoparticle system that was shown to be stable at neutral pH but releases ibuprofen in alkaline conditions

Item Type:	Preprint
DOI/Identification number:	10.26434/chemrxiv.9884114.v1
Refereed:	No
Other identifier:	https://chemrxiv.org/engage/chemrxiv/article-detai...
Name of pre-print platform:	chemRxiv
Subjects:	Q Science > QD Chemistry
Institutional Unit:	Schools > School of Engineering, Mathematics and Physics > Physics and Astronomy
Former Institutional Unit:	Divisions > Division of Natural Sciences > Physics and Astronomy
Depositing User:	Christopher Serpell
Date Deposited:	07 Nov 2019 14:15 UTC
Last Modified:	20 May 2025 09:45 UTC
Resource URI:	https://kar.kent.ac.uk/id/eprint/78374 (The current URI for this page, for reference purposes)

University of Kent Author Information

Shehata, Sara.

Creator's ORCID:
CReDIT Contributor Roles:

Serpell, Christopher.

Creator's ORCID:	https://orcid.org/0000-0002-2848-9077
CReDIT Contributor Roles:

Biagini, Stefano.

Creator's ORCID:	https://orcid.org/0000-0002-4713-5127
CReDIT Contributor Roles:

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