Towards high speed needle microscopy through a multimode fiber by single pixel imaging

We present a proof of concept for microscopy through a multimode fiber using single pixel imaging. We present two implementations, one using galvo scanners and a diffuser plate and one using a digital micromirror device (DMD). Using these setups we can generate thousands of distinct speckle patterns at the distal end of a 50 micron core fiber as illumination patterns for single pixel imaging. We show that the correlation between speckle patterns can be made as low as 30% and the repeatability as high as 98% for a sample of 3200 patterns, and show example single pixel images using a distal detector.