Johnson, Colin G. (1998) Between-host evolution of mutation-rate and within-host evolution of virulence. In: Proceedings Third German Workshop on Artificial Life. . Harri Deutsch (KAR id:71010)
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Abstract
It has been recently realised that parasite virulence (the harm caused by parasites to their hosts) can be an adaptive trait. Selection for a particular level of virulence can happen either at the level of between-host tradeoffs or as a result of short-sighted within-host competition. This paper describes some simulations which study the effect that modifier genes for changes in mutation rate have on suppressing this short-sighted development of virulence, and investigates the interaction between this and a simplified model of immune clearance.
| Item Type: | Conference or workshop item (Paper) |
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| Subjects: | Q Science > QA Mathematics (inc Computing science) > QA 76 Software, computer programming, |
| Institutional Unit: | Schools > School of Computing |
| Former Institutional Unit: |
Divisions > Division of Computing, Engineering and Mathematical Sciences > School of Computing
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| Depositing User: | Colin Johnson |
| Date Deposited: | 13 Dec 2018 16:24 UTC |
| Last Modified: | 20 May 2025 10:23 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/71010 (The current URI for this page, for reference purposes) |
University of Kent Author Information
Johnson, Colin G..
| Creator's ORCID: |
 https://orcid.org/0000-0002-9236-6581
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