Abdelkader, Mohamed S. A., Philippon, Thomas, Asenjo, Juan A., Bull, Alan T., Goodfellow, Michael, Ebel, Rainer, Jaspars, Marcel, Rateb, Mostafa E. (2018) Asenjonamides A–C, antibacterial metabolites isolated from Streptomyces asenjonii strain KNN 42.f from an extreme-hyper arid Atacama Desert soil. The Journal of Antibiotics, . ISSN 0021-8820. E-ISSN 1881-1469). (doi:10.1038/s41429-017-0012-0) (KAR id:65804)
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| Official URL: https://doi.org/10.1038/s41429-017-0012-0 |
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Abstract
Bio-guided fractionation of the culture broth extract of Streptomyces asenjonii strain KNN 42.f recovered from an extreme hyper-arid Atacama Desert soil in northern Chile led to the isolation of three new bioactive ?-diketones; asenjonamides A–C (1–3) in addition to the known N-(2-(1H-indol-3-yl)-2-oxoethyl)acetamide (4), a series of bioactive acylated 4-aminoheptosyl-?-N-glycosides; spicamycins A–E (5–9), and seven known diketopiperazines (10–16). All isolated compounds were characterized by HRESIMS and NMR analyses and tested for their antibacterial effect against a panel of bacteria.
| Item Type: | Article |
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| DOI/Identification number: | 10.1038/s41429-017-0012-0 |
| Subjects: | Q Science |
| Divisions: | Divisions > Division of Natural Sciences > Biosciences |
| Depositing User: | Susan Davies |
| Date Deposited: | 29 Jan 2018 12:12 UTC |
| Last Modified: | 05 Nov 2024 11:03 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/65804 (The current URI for this page, for reference purposes) |
University of Kent Author Information
Bull, Alan T..
| Creator's ORCID: |
 https://orcid.org/0000-0001-6223-7722
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