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Expression of MyHC isoforms mRNA transcripts in different regions of the masseter and medial pterygoid muscles in chimpanzees

Ciurana, Neus, Artells, Rosa, Muñoz, Carmen, Arias-Martorell, Júlia, Bello-Hellegouarch, Gaëlle, Pérez-Pérez, Alejandro, Pastor, Juan Francisco, Potau, Josep Maria (2017) Expression of MyHC isoforms mRNA transcripts in different regions of the masseter and medial pterygoid muscles in chimpanzees. Archives of Oral Biology, 83 . pp. 63-67. ISSN 0003-9969. (doi:10.1016/j.archoralbio.2017.07.003) (KAR id:62876)

Abstract

Objective

The aim of this study is to examine the expression pattern of the different myosin heavy chain (MyHC) isoforms in the masseter and medial pterygoid muscles by real time quantitative polymerase chain reaction (RT-qPCR) to obtain information at molecular level which can be related to the functional characteristics of these two muscles.

Design

The masseter, deep and superficial portion, and medial pterygoid muscles of five adult Pan troglodytes were dissected in order to obtain samples of the anterior and posterior regions of each portion of the

masseter and of the medial pterygoid. The expression of MyHC isoforms mRNA transcripts was analyzed by RT-qPCR.

Results

No significant differences in expression of MyHC isoforms between the masseter and the medial pterygoid were found. In contrast, when comparing the superficial and the deep portion of the masseter, we found that the MyHC-IIM isoform was expressed at a significantly higher level in the superficial portion.

Conclusions

The superficial portion of the masseter and the medial pterygoid muscle have the same expression pattern regarding the different MyHC isoforms. On the other hand, the deep portion of the masseter, which is activated mainly during lateral and repositioning movements of the mandible, has a lower MyHC-IIM isoform expression than the superficial portion. Our findings provide new data on functional aspects of the masseter and medial pterygoid that can complement results obtained by other techniques.

Item Type: Article
DOI/Identification number: 10.1016/j.archoralbio.2017.07.003
Uncontrolled keywords: MasseterMedial pterygoidMyosin heavy chainRT-qPCR
Divisions: Divisions > Division of Human and Social Sciences > School of Anthropology and Conservation
Depositing User: Matthias Werner
Date Deposited: 17 Aug 2017 11:49 UTC
Last Modified: 08 Dec 2022 23:21 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/62876 (The current URI for this page, for reference purposes)

University of Kent Author Information

Arias-Martorell, Júlia.

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