Effect of the Growth Medium on the In Vitro Antifungal Activity of Micafungin (FK-463) against Clinical Isolates of Candida Dubliniensis

Muller, F.M., Kurzai, Oliver, Hacker, J., Frosch, M., Mühlschlegel, Fritz A. (2001) Effect of the Growth Medium on the In Vitro Antifungal Activity of Micafungin (FK-463) against Clinical Isolates of Candida Dubliniensis. Journal of Antimicrobial Chemotherapy, 48 (5). pp. 713-715. ISSN 0305-7453. (doi:10.1093/jac/48.5.713) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:6196)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided.
Official URL: https://doi.org/10.1093/jac/48.5.713

Abstract

Micafungin (FK-463), a member of the new candin family of antifungal agents, was highly active against clinical isolates of Candida albicans and Candida dubliniensis. The in vitro activity of micafungin suggested that it was more potent than fluconazole, flucytosine, amphotericin B or voriconazole against C. albicans, and comparable or moderately less effective against C. dubliniensis isolates when high-resolution medium (HR) was used. Lower MICs of micafungin were recorded when RPMI 2% or AM3 2% media were used, indicating an influence of the growth medium on the MIC.

Item Type:	Article
DOI/Identification number:	10.1093/jac/48.5.713
Additional information:	0305-7453 (Print) Comparative Study Journal Article Research Support, Non-U.S. Gov't
Uncontrolled keywords:	Antibiotics, Antifungal/pharmacology Candida/drug effects/growth & development/isolation & purification Candida albicans/drug effects/growth & development/isolation & purification Culture Media/pharmacology Echinocandins Humans Lipoproteins/pharmacology Peptides, Cyclic/*pharmacology
Subjects:	Q Science
Divisions:	Divisions > Division of Natural Sciences > Biosciences
Depositing User:	Fritz Muhlschlegel
Date Deposited:	28 Oct 2008 19:05 UTC
Last Modified:	05 Nov 2024 09:38 UTC
Resource URI:	https://kar.kent.ac.uk/id/eprint/6196 (The current URI for this page, for reference purposes)

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Mühlschlegel, Fritz A..

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