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Upgrading molecular cytogenetics to study reproduction and reproductive isolation in mammals, birds, and dinosaurs

O'Connor, Rebecca, Damas, J, Farré, Marta, Romanov, Michael N, Martell, Henry, Fonseka, Gothami, Jennings, R, Kiazam, L, Bennett, Sophie, Ward, Jake, and others. (2016) Upgrading molecular cytogenetics to study reproduction and reproductive isolation in mammals, birds, and dinosaurs. Cytogenetic and Genome Research, 148 (2–3). 151-152 (Abstract VII.13). ISSN 1424-8581. E-ISSN 1424-859X. (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:57004)

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http://dx.doi.org/10.1159/000446523

Abstract

The past 10–15 years have seen a revolution in the field of genomics, first with the human genome project, followed by those of key model and agricultural species (chicken, pig, cattle, sheep) and, most recently, ? 60 de novo avian genome assemblies. The ultimate aim of a genome assembly is to create a contiguous unbroken length of sequence from p- to q-terminus to facilitate studies of gene mapping, trait linkage, phylogenomics, and gross genomic organization/change. Chromosome rearrangements are biologically relevant both in the context of reduction in reproductive capability of individual animals and in the establishment in reproductive isolation as species evolve and diverge. Moreover, a karyotype effectively represents a low-resolution map of the genome of any species. In investigating all these aspects, FISH remains the tool of choice, and this study describes a step change in its use.

Item Type: Article
Subjects: Q Science > QH Natural history
Q Science > QH Natural history > QH426 Genetics
Q Science > QL Zoology
Q Science > QP Physiology (Living systems) > QP506 Molecular biology
Divisions: Divisions > Division of Natural Sciences > School of Biosciences
Signature Themes: Food Systems, Natural Resources and Environment
Depositing User: Mike Romanov
Date Deposited: 27 Aug 2016 12:25 UTC
Last Modified: 31 Jul 2021 11:26 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/57004 (The current URI for this page, for reference purposes)
O'Connor, Rebecca: https://orcid.org/0000-0002-4270-970X
Farré, Marta: https://orcid.org/0000-0001-9170-5767
Romanov, Michael N: https://orcid.org/0000-0003-3584-4644
Fowler, Katie E.: https://orcid.org/0000-0003-0359-2390
Larkin, Denis M.: https://orcid.org/0000-0001-7859-6201
Griffin, Darren K.: https://orcid.org/0000-0001-7595-3226
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