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Codon Reassignment and the Evolving Genetic Code: Problems and Pitfalls in Post-genome Analysis

O'Sullivan, Justin M., Davenport, J. Bernard, Tuite, Mick F. (2001) Codon Reassignment and the Evolving Genetic Code: Problems and Pitfalls in Post-genome Analysis. Trends in Genetics, 17 (1). pp. 20-22. ISSN 0168-9525. (doi:10.1016/S0168-9525(00)02144-2) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:5464)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi./10.1016/S0168-9525(00)02144-2

Abstract

The in silico translation of open reading frames, using the 'universal genetic code', must be approached with caution. The uncovering of a number of codon reassignments in nuclear and organellar genomes highlights the importance of experimentally confirming the assignments of all 64 codons for the species whose genome is under investigation. Such alterations to codon meaning also suggest that the genetic code is not 'frozen' and continues to evolve.

Item Type: Article
DOI/Identification number: 10.1016/S0168-9525(00)02144-2
Additional information: 0168-9525 (Print) Journal Article
Uncontrolled keywords: *Codon *Genetic Code *Genome, Bacterial *Genome, Fungal RNA Editing
Subjects: Q Science > QR Microbiology
Divisions: Divisions > Division of Natural Sciences > School of Biosciences
Depositing User: Michael Tuite
Date Deposited: 28 Oct 2008 18:35 UTC
Last Modified: 06 May 2020 03:01 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/5464 (The current URI for this page, for reference purposes)
Tuite, Mick F.: https://orcid.org/0000-0002-5214-540X
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