O'Sullivan, Justin M., Davenport, J. Bernard, Tuite, Mick F. (2001) Codon Reassignment and the Evolving Genetic Code: Problems and Pitfalls in Post-genome Analysis. Trends in Genetics, 17 (1). pp. 20-22. ISSN 0168-9525. (doi:10.1016/S0168-9525(00)02144-2) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:5464)
| The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. | |
| Official URL: http://dx.doi./10.1016/S0168-9525(00)02144-2 |
Abstract
The in silico translation of open reading frames, using the 'universal genetic code', must be approached with caution. The uncovering of a number of codon reassignments in nuclear and organellar genomes highlights the importance of experimentally confirming the assignments of all 64 codons for the species whose genome is under investigation. Such alterations to codon meaning also suggest that the genetic code is not 'frozen' and continues to evolve.
| Item Type: | Article |
|---|---|
| DOI/Identification number: | 10.1016/S0168-9525(00)02144-2 |
| Additional information: | 0168-9525 (Print) Journal Article |
| Uncontrolled keywords: | *Codon *Genetic Code *Genome, Bacterial *Genome, Fungal RNA Editing |
| Subjects: | Q Science > QR Microbiology |
| Divisions: | Divisions > Division of Natural Sciences > Biosciences |
| Depositing User: | Michael Tuite |
| Date Deposited: | 28 Oct 2008 18:35 UTC |
| Last Modified: | 05 Nov 2024 09:37 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/5464 (The current URI for this page, for reference purposes) |
University of Kent Author Information
Tuite, Mick F..
| Creator's ORCID: |
 https://orcid.org/0000-0002-5214-540X
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