Kosmidis, K., Russell, C.D., Black, R.A., Dobre, George, Podoleanu, Adrian G.H. (2006) Flying spot en-face OCT for monitoring cell distribution in collagen-based constructs. In: SPIE Proceedings Series. Proceedings of SPIE - The International Society for Optical Engineering. 6079. Spie-Int Soc Optical Engineering ISBN 0-8194-6121-0. (doi:10.1117/12.648886) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:49753)
| The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. | |
| Official URL: http://dx.doi.org/10.1117/12.648886 |
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| Additional URLs: |
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Abstract
The use of optical coherence tomography (OCT) as a monitoring tool in the growth of human fibroblasts cells in collagen-based constructs is investigated. Rat-tail tendon type-1 collagen based gels mixed with human fibroblasts were prepared and incubated. Fixed samples were then imaged using OCT, and subsequently cross-sectioned and analysed microscopically. The concentration of cells in samples under different contraction dynamics was investigated using analysis of the OCT images. Results show clear differences in scattering intensity as a consequence of cell concentration in both OCT images and micrographs.
| Item Type: | Conference or workshop item (Proceeding) |
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| DOI/Identification number: | 10.1117/12.648886 |
| Uncontrolled keywords: | Cell distribution, Collagen gels, Optical Coherence Tomography, Tissue Engineering, |
| Subjects: |
Q Science > QC Physics R Medicine > R Medicine (General) > R857.O6 Optical instruments |
| Institutional Unit: | Schools > School of Engineering, Mathematics and Physics > Physics and Astronomy |
| Former Institutional Unit: |
Divisions > Division of Natural Sciences > Physics and Astronomy
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| Depositing User: | Giles Tarver |
| Date Deposited: | 24 Jul 2015 14:53 UTC |
| Last Modified: | 20 May 2025 09:38 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/49753 (The current URI for this page, for reference purposes) |
University of Kent Author Information
Dobre, George.
| Creator's ORCID: |
 https://orcid.org/0000-0002-5695-2591
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| CReDIT Contributor Roles: |
Podoleanu, Adrian G.H..
| Creator's ORCID: |
https://orcid.org/0000-0002-4899-9656
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| CReDIT Contributor Roles: |
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