Swept source optical coherence tomography Gabor fusion splicing technique for microscopy of thick samples using a deformable mirror

Costa, C. and Bradu, Adrian and Rogers, J. and Phelan, P. and Podoleanu, Adrian G.H. (2015) Swept source optical coherence tomography Gabor fusion splicing technique for microscopy of thick samples using a deformable mirror. Journal of Biomedical Optics, 20 (1). 016012-016012. ISSN 1083-3668. (doi:https://doi.org/10.1117/1.JBO.20.1.016012) (Full text available)

Abstract

We present a swept source optical coherence tomography (OCT) system at 1060 nm equipped with a wavefront sensor at 830 nm and a deformable mirror in a closed-loop adaptive optics (AO) system. Due to the AO correction, the confocal profile of the interface optics becomes narrower than the OCT axial range, restricting the part of the B-scan (cross section) with good contrast. By actuating on the deformable mirror, the depth of the focus is changed and the system is used to demonstrate Gabor filtering in order to produce B-scan OCT images with enhanced sensitivity throughout the axial range from a Drosophila larvae. The focus adjustment is achieved by manipulating the curvature of the deformable mirror between two user-defined limits. Particularities of controlling the focus for Gabor filtering using the deformable mirror are presented. © 2015 Society of Photo-Optical Instrumentation Engineers.

Item Type: Article
Uncontrolled keywords: adaptive optics, confocal microscopy, optical coherence tomography, Confocal microscopy, Deformation, Mirrors, Optical tomography, Tomography, Closed-loop adaptive optics, Deformable mirrors, Enhanced sensitivity, Focus adjustment, Fusion splicing, Gabor filtering, Swept source optical coherence tomographies, Wave front sensors, Adaptive optics
Subjects: Q Science > QC Physics
Q Science > QC Physics > QC355 Optics
R Medicine > R Medicine (General) > R857.O6 Optical coherence tomography
Divisions: Faculties > Sciences > School of Physical Sciences > Applied Optics Group
Depositing User: Giles Tarver
Date Deposited: 10 Jul 2015 10:07 UTC
Last Modified: 21 Aug 2015 08:29 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/49270 (The current URI for this page, for reference purposes)
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