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Swept source optical coherence tomography Gabor fusion splicing technique for microscopy of thick samples using a deformable mirror

Costa, C., Bradu, Adrian, Rogers, J., Phelan, P., Podoleanu, Adrian G.H. (2015) Swept source optical coherence tomography Gabor fusion splicing technique for microscopy of thick samples using a deformable mirror. Journal of Biomedical Optics, 20 (1). Article Number 016012. ISSN 1083-3668. (doi:10.1117/1.JBO.20.1.016012) (KAR id:49270)

Abstract

We present a swept source optical coherence tomography (OCT) system at 1060 nm equipped with a wavefront sensor at 830 nm and a deformable mirror in a closed-loop adaptive optics (AO) system. Due to the AO correction, the confocal profile of the interface optics becomes narrower than the OCT axial range, restricting the part of the B-scan (cross section) with good contrast. By actuating on the deformable mirror, the depth of the focus is changed and the system is used to demonstrate Gabor filtering in order to produce B-scan OCT images with enhanced sensitivity throughout the axial range from a Drosophila larvae. The focus adjustment is achieved by manipulating the curvature of the deformable mirror between two user-defined limits. Particularities of controlling the focus for Gabor filtering using the deformable mirror are presented. © 2015 Society of Photo-Optical Instrumentation Engineers.

Item Type: Article
DOI/Identification number: 10.1117/1.JBO.20.1.016012
Uncontrolled keywords: adaptive optics, confocal microscopy, optical coherence tomography, Confocal microscopy, Deformation, Mirrors, Optical tomography, Tomography, Closed-loop adaptive optics, Deformable mirrors, Enhanced sensitivity, Focus adjustment, Fusion splicing, Gabor filtering, Swept source optical coherence tomographies, Wave front sensors, Adaptive optics
Subjects: Q Science > QC Physics
Q Science > QC Physics > QC355 Optics
R Medicine > R Medicine (General) > R857.O6 Optical instruments
Divisions: Divisions > Division of Natural Sciences > Physics and Astronomy
Depositing User: Giles Tarver
Date Deposited: 10 Jul 2015 10:07 UTC
Last Modified: 05 Nov 2024 10:33 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/49270 (The current URI for this page, for reference purposes)

University of Kent Author Information

Costa, C..

Creator's ORCID:
CReDIT Contributor Roles:

Bradu, Adrian.

Creator's ORCID: https://orcid.org/0000-0002-6890-1599
CReDIT Contributor Roles:

Podoleanu, Adrian G.H..

Creator's ORCID: https://orcid.org/0000-0002-4899-9656
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