Hobley, G., Gubala, V., Rivera-Sánchez, M.D.C., Rivera, J.M. (2008) Synthesis of 8-heteroaryl-2'-deoxyguanosine derivatives. Synlett, (10). pp. 1510-1514. ISSN 0936-5214. (doi:10.1055/s-2007-1077795) (KAR id:45246)
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| Official URL: http://dx.doi.org/10.1055/s-2007-1077795 |
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Abstract
We describe the synthesis of 8-heteroaromatic-2'-deoxyguanosine analogues using Suzuki-Miyaura or Stille conditions. Unprotected and protected 8-bromo-2â?²-deoxyguanosine was coupled with commercially available heteroarylboronic acids or the trialkyltin derivatives of 2-pyridylbromides either with or without microwave irradiation in good yields.
| Item Type: | Article |
|---|---|
| DOI/Identification number: | 10.1055/s-2007-1077795 |
| Additional information: | Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Synlett [Field not mapped to EPrints] AD - Department of Chemistry, College of Natural Sciences, University of Puerto Rico, Rio Piedras Campus, San Juan 00931, Puerto Rico [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints] |
| Uncontrolled keywords: | Coupling, Nucleobases, Nucleosides, Palladium, Stille reaction, 8 bromo 2' deoxyguanosine, alkyl group, boronic acid derivative, deoxyguanosine derivative, polycyclic aromatic hydrocarbon derivative, pyridine derivative, tin derivative, article, chemical reaction, microwave irradiation, quantum yield, reaction analysis, Stille reaction, suzuki miyaura reaction, synthesis |
| Divisions: | Divisions > Division of Natural Sciences > Medway School of Pharmacy |
| Depositing User: | Vladimir Gubala |
| Date Deposited: | 14 Dec 2017 21:27 UTC |
| Last Modified: | 05 Nov 2024 10:29 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/45246 (The current URI for this page, for reference purposes) |
University of Kent Author Information
Gubala, V..
| Creator's ORCID: |
 https://orcid.org/0000-0001-6301-3632
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