Wagner, Marcell, Abdel-Mageed, Wael M., Ebel, Rainer, Bull, Alan T., Goodfellow, Michael, Fiedler, Hans-Peter, Jaspars, Marcel (2014) Dermacozines H–J Isolated from a Deep-Sea Strain of Dermacoccus abyssi from Mariana Trench Sediments. Journal of Natural Products, 77 (2). pp. 416-420. ISSN 0163-3864. (doi:10.1021/np400952d) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:41068)
| The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. | |
| Official URL: http://dx.doi.org/10.1021/np400952d |
Abstract
Dermacoccus abyssi sp. nov. strains MT1.1 and MT1.2 are actinomycetes isolated from a Mariana Trench sediment at a depth of 10?898 m. The fermentation process using complex media led to the production of three new pigmented heteroaromatic (oxidized and reduced) phenazine compounds, dermacozines H–J (1–3). Extensive use was made of 1D and 2D NMR experiments and high-resolution MS to determine the structures of the compounds. The new dermacozines showed radical scavenging activity, and the highest activity was observed for dermacozine H (1), with an IC50 value of 18.8 ?M.
| Item Type: | Article |
|---|---|
| DOI/Identification number: | 10.1021/np400952d |
| Subjects: | Q Science |
| Divisions: | Divisions > Division of Natural Sciences > Biosciences |
| Depositing User: | Susan Davies |
| Date Deposited: | 13 May 2014 13:30 UTC |
| Last Modified: | 05 Nov 2024 10:25 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/41068 (The current URI for this page, for reference purposes) |
University of Kent Author Information
Bull, Alan T..
| Creator's ORCID: |
 https://orcid.org/0000-0001-6223-7722
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