A study of association between genetic markers in candidate genes and reproductive traits in one generation of a commercial broiler breeder hen population

Dunn, I C and Miao, Yi-Wei and Morris, A and Romanov, Michael N and Wilson, P W and Waddington, David (2004) A study of association between genetic markers in candidate genes and reproductive traits in one generation of a commercial broiler breeder hen population. Heredity, 92 (2). pp. 128-134. ISSN 0018-067X. (doi:https://doi.org/10.1038/sj.hdy.6800396) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)

PDF (Restricted due to publisher copyright policy) - Publisher pdf
Restricted to Repository staff only
Contact us about this Publication Download (159kB)
[img]
Official URL
http://dx.doi.org/10.1038/sj.hdy.6800396

Abstract

Markers of alleles for three physiological candidate genes for reproductive traits, growth hormone (GHR), gonadotropin-releasing hormone receptor (GNRHR) and neuropeptide Y (NPY) were assessed for the association with the total egg production, number of double-yolked eggs and age at first egg in a single generation of a broiler breeder (Gallus gallus) pedigree dam line. Single-nucleotide polymorphisms and deletions were detected in the GHR, GNRHR and NPY genes. Genotypes were identified using a PCR-RFLP assay. The frequency of restriction enzyme+/-alleles in the population was for GHR 0.68 (NspI-) and 0.32 (NspI+), for NPY 0.78 (DraI+) and 0.22 (DraI-) and for GNRHR 0.54 (Bpu11021+) and 0.46 (Bpu11021-). Trait data from a total of 772 hens in 67 sire families from one generation of the pedigree dam line were recorded. However, the analysis used only the offspring of heterozygous sires to reduce the influence of selection and genetic background (n = 33 sire families for GHR; n = 14 sire families for NPY; n = 36 sire families for GNRHR). A dominance effect of NPY on age at first egg and an additive effect of GNRHR on the number of double-yolked eggs were found (P < 0.05).

Item Type: Article
Uncontrolled keywords: Gallus gallus; candidate genes; association; reproduction; SNP
Subjects: Q Science > QH Natural history > QH426 Genetics
Divisions: Faculties > Sciences > School of Biosciences > Biomedical Research Group
Depositing User: M. Romanov
Date Deposited: 12 Dec 2013 16:56 UTC
Last Modified: 16 Dec 2016 17:41 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/37565 (The current URI for this page, for reference purposes)
Romanov, Michael N: https://orcid.org/0000-0003-3584-4644
  • Depositors only (login required):

Downloads

Downloads per month over past year