von der Haar, Tobias, Tuite, Mick F. (2007) Regulated translational bypass of stop codons in yeast. Trends in Microbiology, 15 (2). pp. 78-86. ISSN 0966-842X. (doi:10.1016/j.tim.2006.12.002) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:3145)
The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. | |
Official URL: http://www.sciencedirect.com/science?_ob=ArticleUR... |
Abstract
Stop codons are used to signal the ribosome to terminate the decoding of an mRNA template. Recent studies on translation termination in the yeast Saccharomyces cerevisiale have not only enabled the identification of the key components of the termination machinery, but have also revealed several regulatory mechanisms that might enable the controlled synthesis of C-terminally extended polypeptides via stop-codon readthrough. These include both genetic and epigenetic mechanisms. Rather than being a translation 'error', stop-codon readthrough can have important effects on other cellular processes such as mRNA degradation and, in some cases, can confer a beneficial phenotype to the cell
Item Type: | Article |
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DOI/Identification number: | 10.1016/j.tim.2006.12.002 |
Subjects: | Q Science > QR Microbiology |
Divisions: | Divisions > Division of Natural Sciences > Biosciences |
Depositing User: | Maureen Cook |
Date Deposited: | 14 May 2008 07:14 UTC |
Last Modified: | 05 Nov 2024 09:34 UTC |
Resource URI: | https://kar.kent.ac.uk/id/eprint/3145 (The current URI for this page, for reference purposes) |
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