The patterning and alignment of muscle cells using the selective adhesion of poly(oligoethylene glycol methyl ether methacrylate)-based ABA block copolymers

Popescu, Daniela C., Lems, R., Rossi, Nicholas A. A., Yeoh, Chert-Tsun, Loos, J., Holder, Simon J., Bouten, C.V.C., Sommerdijk, Najm (2005) The patterning and alignment of muscle cells using the selective adhesion of poly(oligoethylene glycol methyl ether methacrylate)-based ABA block copolymers. Advanced Materials, 17 (19). 2324-+. ISSN 0935-9648. (doi:10.1002/adma.200500039) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:2563)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided.
Official URL: http://dx.doi.org/10.1002/adma.200500039

Abstract

The selective adhesion/delamination behavior of poly(oligoethylene glycol methyl ether methacrylate)-based ABA block copolymers is exploited to generate patterned substrates consisting of alternating lanes of glass and copolymer-coated gold. These patterns have been successfully used for the patterning and alignment of C2C12 muscle cells. The parallel-oriented myotubes (see Figure) contract upon electrical stimulation, forming a promising 2D in-vitro model for muscles.

Item Type:	Article
DOI/Identification number:	10.1002/adma.200500039
Additional information:	42 WILEY-V C H VERLAG GMBH
Subjects:	Q Science > QD Chemistry
Institutional Unit:	Schools > School of Engineering, Mathematics and Physics > Physics and Astronomy
Former Institutional Unit:	Divisions > Division of Natural Sciences > Physics and Astronomy
Depositing User:	Simon Holder
Date Deposited:	29 Aug 2008 15:01 UTC
Last Modified:	20 May 2025 09:29 UTC
Resource URI:	https://kar.kent.ac.uk/id/eprint/2563 (The current URI for this page, for reference purposes)

University of Kent Author Information

Holder, Simon J..

Creator's ORCID:	https://orcid.org/0000-0001-8977-9257
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