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Does obesity compromise survival in women with breast cancer?

Carmichael, Amtul R, Bendall, Susan, Lockerbie, Lona, Prescott, R.J., Bates, Tom (2004) Does obesity compromise survival in women with breast cancer? The Breast, 13 . pp. 93-96. ISSN 0960-9776. (doi:10.1016/j.breast.2003.03.002) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:23630)

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Abstract

Summary Obesity, measured by high body mass index (BMI430 kg/m2) is associated

with an increased risk of postmenopausal breast cancer but the effect of obesity

on prognosis is not clear. A prospectively accrued and regularly validated database

of 1579 patients with breast cancer treated in a district general hospital between

1963 and 1999 was analysed for clinical and pathological tumour characteristics

including the family history, grade, tumour type, treatment and outcome. The

risk factors and outcome of obese and non-obese patients were compared.

Breast cancer in obese women was associated with significantly larger tumour

size and worse Nottingham prognostic index. There was no statistically

significant difference in overall and disease-free survival between obese and nonobese

group. Hazard ratios (95% Cl) were 0.81 (0.62–1.06) and 0.80 (0.63–1.01),

respectively. In the present study, obesity is not an indicator of worst prognosis of breast cancer.

Item Type: Article
DOI/Identification number: 10.1016/j.breast.2003.03.002
Subjects: R Medicine > RD Surgery
R Medicine
Divisions: Divisions > Directorate of Education > School of Education
Depositing User: Bates Tom
Date Deposited: 29 Jun 2011 13:20 UTC
Last Modified: 16 Nov 2021 10:02 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/23630 (The current URI for this page, for reference purposes)
Bates, Tom: https://orcid.org/0000-0001-5554-1945
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