Carmichael, Amtul R, Bendall, Susan, Lockerbie, Lona, Prescott, R.J., Bates, Tom (2004) Does obesity compromise survival in women with breast cancer? The Breast, 13 . pp. 93-96. ISSN 0960-9776. (doi:10.1016/j.breast.2003.03.002) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:23630)
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Official URL: http://dx.doi.org/10.1016/j.breast.2003.03.002 |
Abstract
Summary Obesity, measured by high body mass index (BMI430 kg/m2) is associated
with an increased risk of postmenopausal breast cancer but the effect of obesity
on prognosis is not clear. A prospectively accrued and regularly validated database
of 1579 patients with breast cancer treated in a district general hospital between
1963 and 1999 was analysed for clinical and pathological tumour characteristics
including the family history, grade, tumour type, treatment and outcome. The
risk factors and outcome of obese and non-obese patients were compared.
Breast cancer in obese women was associated with significantly larger tumour
size and worse Nottingham prognostic index. There was no statistically
significant difference in overall and disease-free survival between obese and nonobese
group. Hazard ratios (95% Cl) were 0.81 (0.62–1.06) and 0.80 (0.63–1.01),
respectively. In the present study, obesity is not an indicator of worst prognosis of breast cancer.
Item Type: | Article |
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DOI/Identification number: | 10.1016/j.breast.2003.03.002 |
Subjects: |
R Medicine > RD Surgery R Medicine |
Divisions: | Divisions > Directorate of Education > School of Education |
Funders: | National Institute of Lymphology (https://ror.org/03vkvz969) |
Depositing User: | Bates Tom |
Date Deposited: | 29 Jun 2011 13:20 UTC |
Last Modified: | 05 Nov 2024 10:03 UTC |
Resource URI: | https://kar.kent.ac.uk/id/eprint/23630 (The current URI for this page, for reference purposes) |
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