The Changing Management of Oesophageal Carcinoma: Survival in a Population Cohort 1985-1994

Bates, Tom and Antoniou, A. and Marshall, R.E.K. and Harrison, Margaret and Bassett, Eryl E. (2008) The Changing Management of Oesophageal Carcinoma: Survival in a Population Cohort 1985-1994. Open Clinical Cancer Journal, 2 . pp. 44-50. ISSN 1874-1894. (doi:https://doi.org/10.2174/1874189400802010044) (Full text available)

Abstract

Background: The management of esophageal carcinoma is changing but before the introduction of chemotherapy and multidisciplinary teams, surgery became more selective. The aim of this study was to confirm this trend and to examine survival in a total population cohort 1985-94. Results: Only a quarter of 413 patients had surgery but from 1989 even fewer were operated on but there were more longterm survivors: 1/51 v. 7/58 (p<0.05). Operative mortality fell from 12% to 6.9 % in the later period (N.S.) and survival post surgery was marginally improved, 15 v. 11 months p = 0.0502. The five year survival rate doubled from 7.8% to 17.2%. Conclusion: Few studies of esophageal cancer include all cases in a defined population. This carries a very poor prognosis but the present cohort shows a slight improvement with more selective surgery and this may serve as a benchmark against which modern multidisciplinary management might be compared.

Item Type: Article
Uncontrolled keywords: Esophageal cancer, Esophagectomy, Radiotherapy, Mortality, Prognosis
Subjects: R Medicine > RD Surgery
R Medicine
Divisions: Faculties > Sciences > School of Mathematics Statistics and Actuarial Science
Faculties > Social Sciences > Centre for Professional Practice
Depositing User: Tom Bates
Date Deposited: 24 Feb 2010 10:47 UTC
Last Modified: 07 Aug 2018 09:20 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/23626 (The current URI for this page, for reference purposes)
Bates, Tom: https://orcid.org/0000-0001-5554-1945
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