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The Changing Management of Oesophageal Carcinoma: Survival in a Population Cohort 1985-1994

Bates, Tom, Antoniou, A., Marshall, R.E.K., Harrison, Margaret, Bassett, Eryl E. (2008) The Changing Management of Oesophageal Carcinoma: Survival in a Population Cohort 1985-1994. Open Clinical Cancer Journal, 2 . pp. 44-50. ISSN 1874-1894. (doi:10.2174/1874189400802010044) (KAR id:23626)

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Background: The management of esophageal carcinoma is changing but before the introduction of

chemotherapy and multidisciplinary teams, surgery became more selective. The aim of this study was to confirm this

trend and to examine survival in a total population cohort 1985-94.

Results: Only a quarter of 413 patients had surgery but from 1989 even fewer were operated on but there were more longterm

survivors: 1/51 v. 7/58 (p<0.05). Operative mortality fell from 12% to 6.9 % in the later period (N.S.) and survival

post surgery was marginally improved, 15 v. 11 months p = 0.0502. The five year survival rate doubled from 7.8% to


Conclusion: Few studies of esophageal cancer include all cases in a defined population. This carries a very poor prognosis

but the present cohort shows a slight improvement with more selective surgery and this may serve as a benchmark against

which modern multidisciplinary management might be compared.

Item Type: Article
DOI/Identification number: 10.2174/1874189400802010044
Uncontrolled keywords: Esophageal cancer, Esophagectomy, Radiotherapy, Mortality, Prognosis
Subjects: R Medicine > RD Surgery
R Medicine
Divisions: Divisions > Division of Computing, Engineering and Mathematical Sciences > School of Mathematics, Statistics and Actuarial Science
Divisions > Directorate of Education > School of Education
Funders: National Institute of Lymphology (
Depositing User: Bates Tom
Date Deposited: 24 Feb 2010 10:47 UTC
Last Modified: 12 Jul 2022 10:40 UTC
Resource URI: (The current URI for this page, for reference purposes)
Bates, Tom:
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