Bates, Tom, Antoniou, A., Marshall, R.E.K., Harrison, Margaret, Bassett, Eryl E. (2008) The Changing Management of Oesophageal Carcinoma: Survival in a Population Cohort 1985-1994. Open Clinical Cancer Journal, 2 . pp. 44-50. ISSN 1874-1894. (doi:10.2174/1874189400802010044) (KAR id:23626)
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| Official URL: http://dx.doi.org/10.2174/1874189400802010044 |
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Abstract
Background: The management of esophageal carcinoma is changing but before the introduction of
chemotherapy and multidisciplinary teams, surgery became more selective. The aim of this study was to confirm this
trend and to examine survival in a total population cohort 1985-94.
Results: Only a quarter of 413 patients had surgery but from 1989 even fewer were operated on but there were more longterm
survivors: 1/51 v. 7/58 (p<0.05). Operative mortality fell from 12% to 6.9 % in the later period (N.S.) and survival
post surgery was marginally improved, 15 v. 11 months p = 0.0502. The five year survival rate doubled from 7.8% to
17.2%.
Conclusion: Few studies of esophageal cancer include all cases in a defined population. This carries a very poor prognosis
but the present cohort shows a slight improvement with more selective surgery and this may serve as a benchmark against
which modern multidisciplinary management might be compared.
| Item Type: | Article |
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| DOI/Identification number: | 10.2174/1874189400802010044 |
| Uncontrolled keywords: | Esophageal cancer, Esophagectomy, Radiotherapy, Mortality, Prognosis |
| Subjects: |
R Medicine > RD Surgery R Medicine |
| Divisions: |
Divisions > Division of Computing, Engineering and Mathematical Sciences > School of Mathematics, Statistics and Actuarial Science Divisions > Directorate of Education > School of Education |
| Funders: | National Institute of Lymphology (https://ror.org/03vkvz969) |
| Depositing User: | Bates Tom |
| Date Deposited: | 24 Feb 2010 10:47 UTC |
| Last Modified: | 05 Nov 2024 10:03 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/23626 (The current URI for this page, for reference purposes) |
University of Kent Author Information
Bates, Tom.
| Creator's ORCID: |
 https://orcid.org/0000-0001-5554-1945
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| CReDIT Contributor Roles: |
Bassett, Eryl E..
| Creator's ORCID: | |
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| CReDIT Contributor Roles: |
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