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A 10-Year Follow-up of a Longitudinal Study of Gallstone Prevalence at Necropsy in South East England

Khan, Hamed N., Harrison, Margaret, Bassett, Eryl E., Bates, Tom (2009) A 10-Year Follow-up of a Longitudinal Study of Gallstone Prevalence at Necropsy in South East England. Digestive Diseases and Sciences, 54 (12). pp. 2736-2741. ISSN 0163-2116. (doi:10.1007/s10620-008-0682-3) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:23593)

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Abstract

The purpose of this study was to examine a

previous increase in male gallstone disease and to consider

the burden of gallstones in a necropsy study with matched

controls over a decade. Gallstone prevalence in 5,050

males fell from 20.2% to 19.1% (P = 0.022) and in 4,125

females fell from 30.4% to 29.0% (P = 0.03). Female

gallstone subjects had a higher BMI than controls 24.5 vs.

23.3 (P\0.01), but males did not. Gallstones were twice

as common in diabetics, but not with coronary heart disease

(CHD). A third of elderly patients of both sexes had

gallstones, but cholecystectomy was more common in

females, 17:10%. Gallstone-related mortality was 0.7%.

The prevalence of gallstones fell slightly. The association

between gallstones and diabetes was confirmed, but not for

CHD, and for BMI this was confined to females. Gallstones

are very common in the elderly, but most are unoperated

and seldom cause death.

Item Type: Article
DOI/Identification number: 10.1007/s10620-008-0682-3
Uncontrolled keywords: Case control, cholecystectomy, coronary heart disease, diabetes, gallstones, necropsy, obesity prevalence
Subjects: R Medicine > RD Surgery
Divisions: Divisions > Division of Computing, Engineering and Mathematical Sciences > School of Mathematics, Statistics and Actuarial Science
Divisions > Directorate of Education > School of Education
Depositing User: Bates Tom
Date Deposited: 15 Jan 2010 12:02 UTC
Last Modified: 16 Nov 2021 10:01 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/23593 (The current URI for this page, for reference purposes)
Bates, Tom: https://orcid.org/0000-0001-5554-1945
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