A 10-Year Follow-up of a Longitudinal Study of Gallstone Prevalence at Necropsy in South East England

Khan, Hamed N., Harrison, Margaret, Bassett, Eryl E., Bates, Tom (2009) A 10-Year Follow-up of a Longitudinal Study of Gallstone Prevalence at Necropsy in South East England. Digestive Diseases and Sciences, 54 (12). pp. 2736-2741. ISSN 0163-2116. (doi:10.1007/s10620-008-0682-3) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)

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The purpose of this study was to examine a previous increase in male gallstone disease and to consider the burden of gallstones in a necropsy study with matched controls over a decade. Gallstone prevalence in 5,050 males fell from 20.2% to 19.1% (P = 0.022) and in 4,125 females fell from 30.4% to 29.0% (P = 0.03). Female gallstone subjects had a higher BMI than controls 24.5 vs. 23.3 (P\0.01), but males did not. Gallstones were twice as common in diabetics, but not with coronary heart disease (CHD). A third of elderly patients of both sexes had gallstones, but cholecystectomy was more common in females, 17:10%. Gallstone-related mortality was 0.7%. The prevalence of gallstones fell slightly. The association between gallstones and diabetes was confirmed, but not for CHD, and for BMI this was confined to females. Gallstones are very common in the elderly, but most are unoperated and seldom cause death.

Item Type: Article
DOI/Identification number: 10.1007/s10620-008-0682-3
Uncontrolled keywords: Case control, cholecystectomy, coronary heart disease, diabetes, gallstones, necropsy, obesity prevalence
Subjects: R Medicine > RD Surgery
Divisions: Faculties > Sciences > School of Mathematics Statistics and Actuarial Science
Faculties > Social Sciences > Centre for Professional Practice
Depositing User: Tom Bates
Date Deposited: 15 Jan 2010 12:02 UTC
Last Modified: 28 May 2019 15:13 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/23593 (The current URI for this page, for reference purposes)
Bates, Tom: https://orcid.org/0000-0001-5554-1945
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