Khan, Hamed N., Harrison, Margaret, Bassett, Eryl E., Bates, Tom (2009) A 10-Year Follow-up of a Longitudinal Study of Gallstone Prevalence at Necropsy in South East England. Digestive Diseases and Sciences, 54 (12). pp. 2736-2741. ISSN 0163-2116. (doi:10.1007/s10620-008-0682-3) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:23593)
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Official URL: http://dx.doi.org/10.1007/s10620-008-0682-3 |
Abstract
The purpose of this study was to examine a
previous increase in male gallstone disease and to consider
the burden of gallstones in a necropsy study with matched
controls over a decade. Gallstone prevalence in 5,050
males fell from 20.2% to 19.1% (P = 0.022) and in 4,125
females fell from 30.4% to 29.0% (P = 0.03). Female
gallstone subjects had a higher BMI than controls 24.5 vs.
23.3 (P\0.01), but males did not. Gallstones were twice
as common in diabetics, but not with coronary heart disease
(CHD). A third of elderly patients of both sexes had
gallstones, but cholecystectomy was more common in
females, 17:10%. Gallstone-related mortality was 0.7%.
The prevalence of gallstones fell slightly. The association
between gallstones and diabetes was confirmed, but not for
CHD, and for BMI this was confined to females. Gallstones
are very common in the elderly, but most are unoperated
and seldom cause death.
Item Type: | Article |
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DOI/Identification number: | 10.1007/s10620-008-0682-3 |
Uncontrolled keywords: | Case control, cholecystectomy, coronary heart disease, diabetes, gallstones, necropsy, obesity prevalence |
Subjects: | R Medicine > RD Surgery |
Divisions: |
Divisions > Division of Computing, Engineering and Mathematical Sciences > School of Mathematics, Statistics and Actuarial Science Divisions > Directorate of Education > School of Education |
Depositing User: | Bates Tom |
Date Deposited: | 15 Jan 2010 12:02 UTC |
Last Modified: | 16 Nov 2021 10:01 UTC |
Resource URI: | https://kar.kent.ac.uk/id/eprint/23593 (The current URI for this page, for reference purposes) |
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