The actin cytoskeleton: a key regulator of apoptosis and ageing?

Gourlay, Campbell W., Ayscough, Kathryn R. (2005) The actin cytoskeleton: a key regulator of apoptosis and ageing? Nature Reviews Molecular Cell Biology, 6 (7). pp. 583-589. (doi:10.1038/nrm1682) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:22643)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided.
Official URL: http://dx.doi.org/10.1038/nrm1682

Abstract

Evidence from many organisms has shown that the accumulation of reactive oxygen species (ROS) has a detrimental effect on cell well-being. High levels of ROS have been linked to programmed cell death pathways and to ageing. Recent reports have implicated changes to the dynamics of the actin cytoskeleton in the release of ROS from mitochondria and subsequent cell death.

Item Type:	Article
DOI/Identification number:	10.1038/nrm1682
Subjects:	Q Science > QH Natural history > QH301 Biology
Divisions:	Divisions > Division of Natural Sciences > Biosciences
Depositing User:	Campbell Gourlay
Date Deposited:	29 Sep 2009 16:12 UTC
Last Modified:	05 Nov 2024 10:01 UTC
Resource URI:	https://kar.kent.ac.uk/id/eprint/22643 (The current URI for this page, for reference purposes)

University of Kent Author Information

Gourlay, Campbell W..

Creator's ORCID:	https://orcid.org/0000-0002-2373-6788
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