Milner, Helen E., Beliveau, Richard, Jarvis, Simon M. (1994) The in situ size of the dopamine transporter is a tetramer as estimated by radiation inactivation. Biochimica Et Biophysica Acta-Biomembranes, 1190 (1). pp. 185-187. ISSN 0005-2736. (doi:10.1016/0005-2736(94)90051-5) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:19913)
| The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. | |
| Official URL: http://dx.doi.org/10.1016/0005-2736(94)90051-5 |
Abstract
Radiation inactivation analysis of the mazindol-sensitive binding of the dopamine transporter inhibitor, [H-3]GBR-12935 to canine striatal membranes yielded a radiation inactivation target size of 278 +/- 16 kDa. This result, in conjunction with other findings in the literature demonstrating that the molecular mass of the dopamine transporter is similar to 70 kDa, suggests that the native form of the dopamine carrier in the neuronal membranes is a tetrameric assembly of identical 70 kDa subunits.
| Item Type: | Article |
|---|---|
| DOI/Identification number: | 10.1016/0005-2736(94)90051-5 |
| Uncontrolled keywords: | dopamine transporter; radiation inactivation; gbr-12935; (canine brain membrane) |
| Subjects: | Q Science > QP Physiology (Living systems) > QP517 Biochemistry |
| Divisions: | Divisions > Division of Natural Sciences > Biosciences |
| Depositing User: | O.O. Odanye |
| Date Deposited: | 06 Jul 2009 19:31 UTC |
| Last Modified: | 05 Nov 2024 09:57 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/19913 (The current URI for this page, for reference purposes) |
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