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Redox-active metal complexes for imaging hypoxic tissues: structure-activity relationships in copper(II) bis(thiosemicarbazone) complexes

Dearling, Jason L. J., Lewis, Jason S., McCarthy, D.W., Welch, Michael J., Blower, Philip J. (1998) Redox-active metal complexes for imaging hypoxic tissues: structure-activity relationships in copper(II) bis(thiosemicarbazone) complexes. Chemical Communications, (22). pp. 2531-2532. ISSN 1359-7345. (doi:10.1039/a805957h) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

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Official URL
http://dx.doi.org/10.1039/a805957h

Abstract

Reduction potential and lipophilicity of the copper(II) bis(thiosemicarbazone) complexes can be independently controlled by alkylation in the diketone backbone and the N-termini of the ligand, allowing optimisation of radiopharmaceuticals strongly selective for hypoxic tissues.

Item Type: Article
DOI/Identification number: 10.1039/a805957h
Subjects: Q Science > QD Chemistry
Divisions: Faculties > Sciences > School of Biosciences
Depositing User: R.F. Xu
Date Deposited: 01 May 2009 16:45 UTC
Last Modified: 28 May 2019 13:55 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/17692 (The current URI for this page, for reference purposes)
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