Dearling, Jason L. J., Lewis, Jason S., McCarthy, D.W., Welch, Michael J., Blower, Philip J. (1998) Redox-active metal complexes for imaging hypoxic tissues: structure-activity relationships in copper(II) bis(thiosemicarbazone) complexes. Chemical Communications, (22). pp. 2531-2532. ISSN 1359-7345. (doi:10.1039/a805957h) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:17692)
| The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. | |
| Official URL: http://dx.doi.org/10.1039/a805957h |
|
Abstract
Reduction potential and lipophilicity of the copper(II) bis(thiosemicarbazone) complexes can be independently controlled by alkylation in the diketone backbone and the N-termini of the ligand, allowing optimisation of radiopharmaceuticals strongly selective for hypoxic tissues.
| Item Type: | Article |
|---|---|
| DOI/Identification number: | 10.1039/a805957h |
| Subjects: | Q Science > QD Chemistry |
| Institutional Unit: | Schools > School of Natural Sciences > Biosciences |
| Former Institutional Unit: |
Divisions > Division of Natural Sciences > Biosciences
|
| Depositing User: | R.F. Xu |
| Date Deposited: | 01 May 2009 16:45 UTC |
| Last Modified: | 20 May 2025 09:14 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/17692 (The current URI for this page, for reference purposes) |
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