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Thermodynamic and kinetic parameters from isothermal heat conduction microcalorimetry

Beezer, Anthony E., Willson, Richard J., Mitchell, John C., Hills, Andrew K., Gaisford, Simon, Wood, Eleanor, Connor, Joseph A. (1998) Thermodynamic and kinetic parameters from isothermal heat conduction microcalorimetry. Pure and Applied Chemistry, 70 (3). pp. 633-638. ISSN 0033-4545. (doi:10.1351/pac199870030633) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1351/pac199870030633

Abstract

Recent developments have led to a general procedure that allows the analysis of microcalorimetric data to determine both kinetic and thermodynamic parameters. This makes microcalorimetry a technique with a potential for the accurate prediction of long-term stability, and excipient compatibility, of pharmaceutical compounds. The data presented here show the uses and limitations of this general method when applied to simple solution phase reactions, that are fast to medium term in duration, and suggest how the method may be extended to more complex heterogeneous systems that reflect cases which may be encountered industrially.

Item Type: Article
DOI/Identification number: 10.1351/pac199870030633
Subjects: Q Science > QD Chemistry
Divisions: Faculties > Sciences > School of Biosciences
Depositing User: I. Ghose
Date Deposited: 05 Oct 2009 07:12 UTC
Last Modified: 07 Jun 2019 12:46 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/17581 (The current URI for this page, for reference purposes)
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