Beezer, Anthony E., Willson, Richard J., Mitchell, John C., Hills, Andrew K., Gaisford, Simon, Wood, Eleanor, Connor, Joseph A. (1998) Thermodynamic and kinetic parameters from isothermal heat conduction microcalorimetry. Pure and Applied Chemistry, 70 (3). pp. 633-638. ISSN 0033-4545. (doi:10.1351/pac199870030633) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:17581)
| The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. | |
| Official URL: http://dx.doi.org/10.1351/pac199870030633 |
Abstract
Recent developments have led to a general procedure that allows the analysis of microcalorimetric data to determine both kinetic and thermodynamic parameters. This makes microcalorimetry a technique with a potential for the accurate prediction of long-term stability, and excipient compatibility, of pharmaceutical compounds. The data presented here show the uses and limitations of this general method when applied to simple solution phase reactions, that are fast to medium term in duration, and suggest how the method may be extended to more complex heterogeneous systems that reflect cases which may be encountered industrially.
| Item Type: | Article |
|---|---|
| DOI/Identification number: | 10.1351/pac199870030633 |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Divisions > Division of Natural Sciences > Biosciences |
| Depositing User: | I. Ghose |
| Date Deposited: | 05 Oct 2009 07:12 UTC |
| Last Modified: | 05 Nov 2024 09:53 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/17581 (The current URI for this page, for reference purposes) |
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