Significant reduction of sperm disomy in six men: effect of traditional Chinese medicine?

Tempest, Helen G., Homa, Sheryl T., Zhai, Xiao-Ping, Griffin, Darren K. (2005) Significant reduction of sperm disomy in six men: effect of traditional Chinese medicine? Asian Journal of Andrology, 7 (4). pp. 419-425. ISSN 1008-682X. (doi:10.1111/j.1745-7262.2005.00068.x) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:12495)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided.
Official URL: http://dx.doi.org/10.1111/j.1745-7262.2005.00068.x

Abstract

AIM: To test the hypothesis that levels of sperm disomy fell significantly in six men treated by traditional Chinese medicine (TCM). METHODS: Fluorescence in situ hybridization (FISH) was done on the sperm heads of six men before and during treatment by TCM. RESULTS: There was a significant reduction in sperm disomy in all six men. This coincided with TCM treatment. CONCLUSION: This is the first study reporting a significant reduction in sperm disomy in men over a given time course. The fact that this coincided with TCM treatment is intriguing but no conclusions can be drawn from this until placebo-controlled clinical trials are implemented.

Item Type:	Article
DOI/Identification number:	10.1111/j.1745-7262.2005.00068.x
Additional information:	10.1111/j.1745-7262.2005.00068.x 1008-682X
Uncontrolled keywords:	Adult Aneuploidy Chromosomes, Human, X Chromosomes, Human, Y Drugs, Chinese Herbal Humans In Situ Hybridization, Fluorescence Infertility, Male Male Medicine, Chinese Traditional Spermatozoa Treatment Outcome
Subjects:	Q Science
Institutional Unit:	Schools > School of Natural Sciences > Biosciences
Former Institutional Unit:	Divisions > Division of Natural Sciences > Biosciences
Depositing User:	Darren Griffin
Date Deposited:	12 Sep 2008 22:56 UTC
Last Modified:	20 May 2025 09:13 UTC
Resource URI:	https://kar.kent.ac.uk/id/eprint/12495 (The current URI for this page, for reference purposes)

University of Kent Author Information

Griffin, Darren K..

Creator's ORCID:	https://orcid.org/0000-0001-7595-3226
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