Bridges, Madelaine, Secchi, Agostina, Whiskey, Eromona, Shergill, Sukhi (2025) A multidisciplinary approach to establishing clozapine in a patient with schizophrenia and comorbid ASD: A case report. BMC Psychiatry, 25 (1). Article Number 1158. ISSN 1471-244X. (doi:10.1186/s12888-025-07280-7) (KAR id:112507)
|
PDF
Publisher pdf
Language: English 
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
|
|
|
Download this file (PDF/631kB) |
Preview |
| Request a format suitable for use with assistive technology e.g. a screenreader | |
| Official URL: https://doi.org/10.1186/s12888-025-07280-7 |
|
Abstract
Background
There is substantial symptom overlap in psychosis and autism spectrum disorder (ASD) and co-morbidity is common. In addition, antipsychotic response may be moderated by the co-occurrence. Individuals with ASD may be at greater risk of some clozapine adverse effects and occasionally, its use may be contra-indicated.
Case presentation
We present the case of a patient with ASD with psychosis unresponsive to multiple antipsychotics, but extra precaution was required with clozapine.
Conclusion
A multidisciplinary approach is required to establish clozapine in a patient with schizophrenia and ASD.
| Item Type: | Article |
|---|---|
| DOI/Identification number: | 10.1186/s12888-025-07280-7 |
| Uncontrolled keywords: | Psychosis, Schizophrenia, Autism spectrum disorder, Case report, Clozapine |
| Subjects: | R Medicine |
| Institutional Unit: | Schools > Kent and Medway Medical School |
| Former Institutional Unit: |
There are no former institutional units.
|
| Funders: | University of Kent (https://ror.org/00xkeyj56) |
| SWORD Depositor: | JISC Publications Router |
| Depositing User: | JISC Publications Router |
| Date Deposited: | 13 Feb 2026 16:08 UTC |
| Last Modified: | 17 Feb 2026 14:36 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/112507 (The current URI for this page, for reference purposes) |
University of Kent Author Information
Shergill, Sukhi.
| Creator's ORCID: |
 https://orcid.org/0000-0003-4928-9100
|
|---|---|
| CReDIT Contributor Roles: |
- Link to SensusAccess
- Export to:
- RefWorks
- EPrints3 XML
- BibTeX
- CSV
- Depositors only (login required):
Altmetric
Altmetric
