Nokhodchi, Ali, Nazemiyeh, H., Ghafourian, Taravat, Hassan-Zadeh, Davood, Valizadeh, Hadi, Bahary, L.A.S. (2002) The effect of glycyrrhizin on the release rate and skin penetration of diclofenac sodium from topical formulations. IL Farmaco, 57 (11). pp. 883-888. ISSN 0014-827X. (doi:10.1016/S0014-827X(02)01298-3) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:10760)
| The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. | |
| Official URL: http://dx.doi.org/10.1016/S0014-827X(02)01298-3 |
Abstract
The influence of glycyrrhizin extracted from Glycyrrhiza glabra var. glandulifera (licorice roots) on the percutaneous absorption
of diclofenac sodium from sodium carboxymethylcellulose (NaCMC) gels or oil-in-water (o/w) emulsion was investigated. Skin
permeation experiments were carried out using excised abdominal rat skin. The results showed that the efficiency of glycyrrhizin as
an enhancer agent is greater in gel formulations than it is in the emulsions. The enhancer with the concentration of 0.1% w/w in gel
increased diclofenac sodium flux value to tenfold compared with the control gel.
# 2002 E´ ditions scientifiques et me´dicales Elsevier SAS
| Item Type: | Article |
|---|---|
| DOI/Identification number: | 10.1016/S0014-827X(02)01298-3 |
| Subjects: |
Q Science Q Science > QD Chemistry |
| Divisions: | Divisions > Division of Natural Sciences > Medway School of Pharmacy |
| Depositing User: | Taravat Ghafourian |
| Date Deposited: | 21 Oct 2008 16:39 UTC |
| Last Modified: | 05 Nov 2024 09:44 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/10760 (The current URI for this page, for reference purposes) |
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