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Genome-wide association study revealed putative SNPs and candidate genes associated with growth and meat traits in Japanese quail

Volkova, Natalia A., Romanov, Michael N., Abdelmanova, Alexandra S., Larionova, Polina V., German, Nadezhda Yu., Vetokh, Anastasia N., Shakhin, Alexey V., Volkova, Ludmila A., Anshakov, Dmitry V., Fisinin, Vladimir I., and others. (2024) Genome-wide association study revealed putative SNPs and candidate genes associated with growth and meat traits in Japanese quail. Genes, 15 (3). Article Number 294. E-ISSN 2073-4425. (doi:10.3390/genes15030294) (KAR id:105127)


The search for SNPs and candidate genes that determine the manifestation of major selected traits is one crucial objective for genomic selection aimed at increasing poultry production efficiency. Here, we report a genome-wide association study (GWAS) for traits characterizing meat performance in the domestic quail. A total of 146 males from an F 2 reference population resulting from crossing a fast (Japanese) and a slow (Texas White) growing breed were examined. Using the genotyping-by-sequencing technique, genomic data were obtained for 115,743 SNPs (92,618 SNPs after quality control) that were employed in this GWAS. The results identified significant SNPs associated with the following traits at 8 weeks of age: body weight (nine SNPs), daily body weight gain (eight SNPs), dressed weight (33 SNPs), and weights of breast (18 SNPs), thigh (eight SNPs), and drumstick (three SNPs). Also, 12 SNPs and five candidate genes (GNAL, DNAJC6, LEPR, SPAG9, and SLC27A4) shared associations with three or more traits. These findings are consistent with the understanding of the genetic complexity of body weight-related traits in quail. The identified SNPs and genes can be used in effective quail breeding as molecular genetic markers for growth and meat characteristics for the purpose of genetic improvement.

Item Type: Article
DOI/Identification number: 10.3390/genes15030294
Uncontrolled keywords: GWAS; genotyping by sequencing; Japanese quail; SNPs; candidate genes; body weight; meat performance traits
Subjects: Q Science > QH Natural history > QH426 Genetics
S Agriculture > SF Animal culture
Divisions: Divisions > Division of Natural Sciences > Centre for Interdisciplinary Studies of Reproduction
Divisions > Division of Natural Sciences > Biosciences
Signature Themes: Food Systems, Natural Resources and Environment
Depositing User: Mike Romanov
Date Deposited: 26 Feb 2024 09:16 UTC
Last Modified: 15 Mar 2024 16:04 UTC
Resource URI: (The current URI for this page, for reference purposes)

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