828 kHz retinal imaging with an 840 nm Fourier domain mode locked laser

Klufts, M., Martinez Jimenez, Alejandro, Lotz, S., Pfeiffer, T., Mlynek, A., Wieser, W., Chamarovskiy, A., Bradu, Adrian, Podoleanu, Adrian G.H., Huber, R. and others. (2023) 828 kHz retinal imaging with an 840 nm Fourier domain mode locked laser. Biomedical Optics Express, 14 (12). pp. 6493-6508. E-ISSN 2156-7085. (doi:10.1364/BOE.504302) (KAR id:104123)

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Official URL: https://doi.org/10.1364/BOE.504302

Abstract

This paper presents a Fourier domain mode locked (FDML) laser centered around 840 nm. It features a bidirectional sweep repetition rate of 828 kHz and a spectral bandwidth of 40 nm. An axial resolution of ∼9.9 μm in water and a 1.4 cm sensitivity roll-off are achieved. Utilizing a complex master-slave (CMS) recalibration method and due to a sufficiently high sensitivity of 84.6 dB, retinal layers of the human eye in-vivo can be resolved during optical coherence tomography (OCT) examination. The developed FDML laser enables acquisition rates of 3D-volumes with a size of 200 × 100 × 256 voxels in under 100 milliseconds. Detailed information on the FDML implementation, its challenging design tasks, and OCT images obtained with the laser are presented in this paper.

Item Type:	Article
DOI/Identification number:	10.1364/BOE.504302
Subjects:	Q Science > QC Physics > QC20 Mathematical Physics R Medicine > R Medicine (General) > R895 Medical physics. Medical radiology. Nuclear medicine
Divisions:	Divisions > Division of Natural Sciences > Physics and Astronomy
Funders:	European Research Council (https://ror.org/0472cxd90)
Depositing User:	Alejandro Martinez Jimenez
Date Deposited:	29 Nov 2023 22:09 UTC
Last Modified:	13 Mar 2024 15:49 UTC
Resource URI:	https://kar.kent.ac.uk/id/eprint/104123 (The current URI for this page, for reference purposes)

University of Kent Author Information

Martinez Jimenez, Alejandro.

Creator's ORCID:	https://orcid.org/0000-0001-5370-7817
CReDIT Contributor Roles:

Bradu, Adrian.

Creator's ORCID:	https://orcid.org/0000-0002-6890-1599
CReDIT Contributor Roles:

Podoleanu, Adrian G.H..

Creator's ORCID:	https://orcid.org/0000-0002-4899-9656
CReDIT Contributor Roles:

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